摘要
为了满足海量的异构肿瘤临床数据处理和肿瘤疾病的多中心协作诊疗需求,利用网格平台建立肿瘤数据互联系统(TDIS),实现虚拟化的肿瘤诊断服务平台,实时共享并规范化管理肿瘤信息。该系统采用Globus Toolkit4.0开发工具搭建开放式网格服务框架,基于Web服务资源框架(WSRF)封装数据资源,利用中间件技术为异构数据交互提供统一的访问接口,以虚拟化服务优化互联交互过程并灵活查询、调用肿瘤信息资源。针对海量异构肿瘤数据,采用联邦存储及多种授权模式的安全服务机制,实时监测及平衡负载。该系统可协同管理多中心的异构肿瘤数据,实现肿瘤患者数据的查询、共享及分析,对比匹配典型病例库或各服务节点的病例信息库资源,协助医生查阅相似病例资料并制定综合的肿瘤治疗方案,有效地提高肿瘤诊治效率,并促进肿瘤协同诊疗模式的发展。
In order to satisfy demands of massive and heterogeneous tumor clinical data processing and the multi-cen- ter collaborative diagnosis and treatment for tumor diseases, a Tumor Data Interacted System （TDIS） was established based on grid platform, so that an implementing virtualization platform of tumor diagnosis service was realized, sharing tumor information in real time and carrying on standardized management. The system adopts Globus Toolkit 4.0 tools to build the open grid service framework and encapsulats data resources based on Web Services Resource Framework （WSRF）. The system uses the middleware technology to provide unified access interface for heterogeneous data interaction, which could optimize interactive process with virtualized service to query and call tumor information resources flexibly. For massive amounts of heterogeneous tumor data,the federated stored and multiple authorized mode is selected as security services mechanism, real-time monitoring and balancing load. The system can cooperatively manage multi-center heterogeneous tumor data to realize the tumor patient data query, sharing and analysis, and compare and match resources in typical clinical database or clinical information database in other service node, thus it can assist doctors in consulting similar case and making up multidisciplinary treatment plan for tumors. Consequently, the system can improve efficiency of diagnosis and treatment for tumor, and promote the development of collaborative tumor diagnosis model.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2016年第3期473-480,共8页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(61101174)
上海市科委医学引导项目(12401907700)
上海市教委重点课程项目
大学生创新训练计划项目(XJ2013237)
微创励志创新基金
