摘要
目的探讨汉坦病毒感染患者不同麻醉方式对术后苏醒的影响,并归纳影响患者苏醒的相关因素,以期选择最佳的方法,提高临床诊治水平。方法选取医院2010年5月-2013年5月30例汉坦病毒感染行手术治疗的患者,根据不同麻醉方式分为观察组15例予配合异氟烷持续吸入,对照组15例予瑞芬太尼泵注配合丙泊酚泵注,比较两组患者的麻醉苏醒相关指标并归纳影响汉坦病毒感染患者术后苏醒的相关因素。结果观察组患者各时期收缩压及舒张压均明显低于对照组,差异有统计学意义(P<0.05);两组于切皮5min及30min时的心率差异无统计学意义,但停止给药以及气管拔管时观察组明显低于对照组,差异有统计学意义(P<0.05);观察组患者苏醒时间和拔管时间均明显短于对照组,拔管后30min的意识形态评分明显高于对照组,差异有统计学意义(P<0.05);拔管后2h观察组出现躁动、延迟复苏以及并发症的比例明显低于对照组,差异有统计学意义(P<0.05);观察组术后轻度认知障碍的比例明显高于对照组,中度及重度认知障碍的比例明显低于对照组,差异有统计学意义(P<0.05)。结论对于汉坦病毒感染且需手术治疗的患者,瑞芬太尼联合异氟烷持续泵注有利于患者早期苏醒,苏醒效果与患者受教育程度和合并症均相关,术前应加以评估。
OBJECTIVE To explore the effects of the different anesthesia approaches on postoperative recovery of patients with Hantavirus infection and conclude the influencing factors for recovery of the patients so as to choose the optimal method and improve the level of clinical diagnosis and treatment.METHODS A total of 30 patients with Hantavirus infection who underwent surgeries from May 2010 to May 2013 were enrolled in the study and divided into the observation group with 15 cases and the control group with 15 cases according to the anesthesia approach.The observation group was treated with pumping infusion of remifentanil combined with continuous inhalation of isoflurane,while the control group was given pumping infusion of remifentanil combined with pumping infusion of propofol.The related indicators for recovery from anesthesia were observed and compared between the two groups of patients,and the influencing factors for the postoperative recovery of the patients with Hantavirus infection were concluded.RESULTS The systolic pressure and diastolic pressure of the observation group were significantly lower than those of the control group during the time periods（P〈0.05）.There was no significant difference in the heart rate between the two groups at 5min or 30 min of skin incision,however,the heart rate of the observation group was significantly lower than that of control group at the time of withdrawal of drugs or removal of endotracheal tube（P〈0.05）.The time of recovery and time of extubation were significantly shorter in the observation group than in the control group;the score of consciousness of the observation group was significantly higher than that of the control group after the extubation for 30min（P〈0.05）.The proportion of the patients with dysphoria,delayed recovery,or complications was significantly lower in the observation group than in the control group after the extubation for 2hours（P〈0.05）.The proportion of the patients with postoperative mild cognitive impairment of the observa
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第12期2808-2810,共3页
Chinese Journal of Nosocomiology
基金
浙江省卫生厅医药卫生计划基金资助项目(2012KYA141)
关键词
汉坦病毒
麻醉方式
苏醒
相关因素
Hantavirus
Anesthesia approach
Recovery
Related factor
