摘要
目的:研究及探讨血浆游离氨基酸及血清miR指标与肝硬化的关系。方法:选取于本院进行诊治的82例肝硬化患者为观察组,并选取同时间段内的82名同龄健康人员为对照组,然后将两组血浆游离氨基酸及血清miR指标进行分别检测,然后将两组中不同分期和分类患者的检测结果进行比较,同时以Logistic分析之间的关系。结果:两组的血浆游离氨基酸及血清miR指标存在明显差异,且不同分期者的上述指标之间也有显著性差异(P<0.05),而不同分类者之间则无明显差异(P>0.05),上述分析指标经Logistic分析与肝硬化有密切的关系。结论:血浆游离氨基酸及血清miR指标均与肝硬化有密切的关系,应加强对肝硬化患者上述指标的监测。
Objective:To study and investigate the relationships between plasma free amino acid,serum miR indexes and hepatocirrhosis.Methods:A total of 82 patients with hepatocirrhosis treated in our hospital were selected as the observation group,82 health persons with the same age were selected as the control group during the same time period,then the plasma free amino acid and serum miR indexes of two groups were respectively detected,and the detection results of control group and observation group,and observation group with different staging and classification were compared,then the relationship between those detection indexes and hepatocirrhosis were analyzed by the Logistic analysis.Results:The plasma free amino acid and serum miR indexes of two groups showed no significant differences,but those indexes of patients with different staging of hepatocirrhosis all showed significant differences(Pall<0.05),while the indexes levels of patients with different classification of hepatocirrhosis showed no significant differences(Pall<0.05).Logistic analysis showed all these indexes were closely correlated with hepatocirrhosis.Conclusion:The plasma free amino acid and serum miR indexes all had close relationship with the hepatocirrhosis,and those indexes of patients with hepatocirrhosis should beclosly monitored.
出处
《海南医学院学报》
CAS
2016年第14期1521-1523,共3页
Journal of Hainan Medical University
