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俯卧位通气对急性呼吸窘迫综合征患者影响的Meta分析 被引量:41

Influence of Ventilation in Prone Position on Patients with Acute Respiratory Distress Syndrome:A Meta Analysis
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摘要 目的评价俯卧位通气对急性呼吸窘迫综合征(acute respiratory distress syndrom,ARDS)患者的影响。方法计算机检索the Cochrane library、PubMed、Embase、Medline、Ovid、CBM、CNKI、维普数据库中截至2013年12月1日所有公开发表的关于ARDS患者俯卧位通气影响的随机对照试验(randomized controlled trial,RCT),并通过纳入文献的参考文献进行引证检索,纳入文献的质量由两名经过专业医学循证培训的医学生完成,对符合质量标准的文献进行Meta分析。结果共纳入12篇RCT,其中7个RCT的研究结果显示,俯卧位通气对患者氧合指数的提高有显著影响[OR=69.65,95%CI(37.13-102.7),P〈0.0001];另外8个研究结果表明,俯卧位通气对降低病死率有显著效果[OR=0.63,95%CI(0.51,0.78),P〈0.001]。结论俯卧位通气可以有效地改善ARDS患者的氧合指数,降低病死率。 Objective To evaluate the influence of prone position ventilation in patients with acute respiratory distress syndrome(ARDS).Method The Cochrane library,PubMed,Embase,Medline,Ovid,CBM,CNKI and Weipu database were searched to gather randomized controlled trials(RCTs)that had been published before December 1st,2013.The qualities of the RCTs were critically appraised by two medical postgraduates independently.Meta-analysis was conducted for the eligible RCTs.Result Totally 12 RCTs were included.Seven studies showed that the prone position ventilation has a significant influence in improving patients oxygenation scores(OR=69.65,95%CI[37.13-102.7],P〈0.001).Another six studied showed that prone position ventilation has a significant effect in reducing mortality(OR=0.63,95%CI[0.51,0.78],P〈0.001).Conclusions Prone position ventilation can effectively improve the patients' oxygenation with ARDS,and reduce the mortality rate.
出处 《解放军护理杂志》 CSCD 2016年第7期20-23,27,共5页 Nursing Journal of Chinese People's Liberation Army
关键词 急性呼吸窘迫综合征 俯卧位通气 META分析 acute respiratory distress syndrome prone position ventilation Meta analysis
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