摘要
目的探讨乳腺癌Auchincloss法与Kodama法淋巴结清扫的利弊。方法将我院收治的150例乳腺癌患者随机分为Auchincloss组75例和Kodama组75例,Auchincloss组术中采用Auchincloss法行淋巴结清扫,Kodama组术中采用Kodama法行淋巴结清扫,比较两组手术情况、并发症发生率及远期生存情况。结果 Kodama组手术时间显著长于Auchincloss组(P<0.05)。术后6个月,Kodama组上肢运动障碍、感觉障碍、胸大肌萎缩发生率均显著低于Auchincloss组(P<0.05)。两组术后主要并发症有皮瓣坏死、淋巴瘘、皮下积液、患肢水肿等,两组并发症发生率比较差异无统计学意义(P>0.05)。Kodama组5年生存率为72.5%,Auchincloss组为77.4%,两组比较差异无统计学意义(P>0.05);两组复发率、远处转移率比较差异亦无统计学意义(P>0.05)。结论 Kodama法能够取得满意的淋巴结清扫效果,且能够保留胸大肌功能神经,值得临床推广。
Objective To explore the advantages and disadvantages of Auchincloss method and Kodama method on lymph node dissection in breast cancer treatment.Methods A total of 150 patients who had been suffering breast cancer and had been admitted to our hospital were randomly divided into Auchincloss group(n=75) and Kodama group(n=75).Auchincloss group was treated with lymph node dissection by Auchincloss method and Kodama group with lymph node dissection by Kodama method.The operation conditions,complications and long-term survival of the two groups were compared.Results The operation duration of Kodama was much longer than that of Auchincloss group(P〈0.05).Six months after the operation,the incidence of upper limb movement disorders,sensory dysfunction and pectoralis major atrophy of Kodama group was much lower than that of Auchincloss group(P〈0.05).The complications of the two groups mainly included skin flap necrosis,lymphatic fistula,subcutaneous effusion and limb edema,etc.There was no statistic difference between the incidence of complications in the two groups(P〈0.05).In addition,there was no statistic difference between the five-year survival rate(72.5% for Kodama group,77.4% for Auchincloss group)(P〈0.05),and recurrence rate and distant metastatic rate(P〉0.05) of the two groups.Conclusion Kodama method has satisfactory effect on lymph node dissection,can protect the functional nerves of pectoralis major and is worth clinical popularizing.
出处
《西南国防医药》
CAS
2016年第6期605-608,共4页
Medical Journal of National Defending Forces in Southwest China