摘要
心力衰竭是心血管疾病患者死亡的重要原因之一,已成为全球心血管疾病治疗新的挑战。药物治疗能改善症状,降低病死率。近年来,越来越多的临床试验和注册研究证据证实,器械治疗能在药物治疗基础上,进一步降低心力衰竭患者的病死率,逆转左室重构,改善生活质量。心力衰竭的器械治疗最初主要是再同步化治疗、植入式心律转复除颤器,近年来还出现了心肌收缩力调节器、左室辅助装置、迷走神经及脊髓刺激等多种器械治疗方式。本文就心力衰竭器械治疗的最新进展进行综述。
Objective:Heart failure, as one of the major reason for cardiovascular death, has emerged as a new challenge for the burden of global cardiovascular disease. Medication therapy can relief symptoms and reduce mortality of heart failure patients. Recently,device-based therapy has been validated by large sample size of clinical trials to be effective treatment by reducing mortalities, reversing ventricular remodeling, and improving life quality of patients with severe heart failure. The present review discussed current devicebased therapies for chronic heart failure including cardiac resynchronization therapy, implantable cardioverter defibrillator, cardiac contractility modulation, percutaneous ventricular restoration, vagus nerve and spinal cord stimulation.
出处
《南京医科大学学报(自然科学版)》
CAS
CSCD
北大核心
2016年第4期385-389,共5页
Journal of Nanjing Medical University(Natural Sciences)
关键词
心力衰竭
器械治疗
心脏再同步治疗
心肌收缩力调节
heart failure
device-based therapy
cardiac resynchronization therapy
cardiac contractility modulation