摘要
目的探讨经皮经肝胆道引流术对肝癌合并阻塞性黄疸患者的临床治疗效果。方法回顾性分析孟州市中医院自2013年1月至2015年1月收治原发性肝癌合并阻塞性黄疸患者60例,诊断明确后因多种原因仅采用PTBD术减黄治疗,未对肿瘤本身进行治疗,对患者手术前后肝功能情况进行对比分析,并计算患者生存时间。结果本组病例手术均获得成功,以术后胆红素水平较术前下降30%为治疗有效,有效率达80%;术后患者总胆红素、直接胆红素值、血清谷丙及谷草转氨酶均较引流前明显下降,但血清白蛋白指标比较差异没有统计学意义;术后1个月生存率为96.7%,2个月生存率为63.3%,3个月生存率为41.7%,4个月生存率为41.7%,5个月生存率为21.7%,6个月生存率为11.7%,7个月生存率为1.7%,中位数为2.5个月。结论肝癌合并阻塞性黄疸患者积极行经皮经肝胆道引流术有利于改善患者肝功能,延长患者生存期。
Objective To investigate the clinical therapeutic effect of percutaneous hepatic biliary drainage in patients with liver cancer with obstructive jaundice. Methods Retrospective analysis of our hospital from January 2013 to 2015 January primary hepatocellular carcinoma complicated with obstruction jaundice patients 60 cases,clearly due to a variety of reasons diagnosis using only PTBD jaundice reducing treatment,did not have treatment on the tumor itself,on the liver function of the patients before and after surgery carries on the contrast analysis,and survival time were calculated. Results This group of cases were successful,with postoperative bilirubin level compared with the preoperative decreased by 30%for the effective treatment of,the effective rate was 80%; Postoperative patients,total bilirubin,direct bilirubin values,serum glutamic Bingji aspartate aminotransferase（ AST） were drainage decreased,but serum albumin index difference was not statistically significant. The survival rate was 96. 7% after 1 month,the survival rate was 63. 3% after 2 month,the survival rate was 41. 7% after 3 months,the survival rate was 41. 7% after 4 months,the survival rate was 21. 7% after 5months,and the survival rate was 11. 7% after 6 months,and the survival rate was in after 7 months,and the survival rate was 1. 7% and the survival rate was 2. 5,and the median was months. Conclusion Patients with liver cancer with obstructive jaundice were treated with percutaneous drainage of liver and biliary drainage was beneficial to improve patients＇ liver function and prolong the survival time of patients with liver cancer.
出处
《医药论坛杂志》
2016年第4期67-70,共4页
Journal of Medical Forum
关键词
原发性肝癌
黄疸
介入治疗
临床疗效
Primary liver cancer
Jaundice
Interventional therapy
Clinical efficacy
