摘要
目的探讨胎儿先天畸形的相关危险因素,提出预防措施。方法 2014年6月1日~2015年1月31日深圳市妇幼保健院孕期产检时发现胎儿畸形的孕妇79例进行调查,分析影响畸形发生的危险因素。结果通过对3997例孕妇产前筛查和随访,确诊79例畸形胎儿,发生率为2.0%,其中神经系统畸形占构成比例最高（35.4%）,其次为循环系统和四肢骨骼,分别占构成比例的22.7%和20.3%;与先天性畸形儿明显相关的危险因素主要包括：围产儿性别、孕妇年龄、孕期吸烟及饮酒暴露等因素,差异有统计学意义（P〈0.05）;而孕妇民族情况与先天性畸形儿发生无相关性,差异无统计学意义（P〉0.05）。结论做好先天性畸形儿的监测,提高优生咨询和产前筛查诊断水平,重点筛查有高危因素的人群,采取适当有效的预防措施,以减少先天性畸形儿的发生,提高我国出生人口素质。
Objective：Discussion of fetal malformation associated risk factors,proposes preventive measures. Methods：Investigating pregnancy check-found 79 cases of fetal malformations in pregnant women in Shenzhen City MCH on June 1,2014-on January31,2015,to analysis of risk factors that affect the occurrence of deformities. Results：By 3997 cases of pregnant women prenatal screening and follow-up,confirmed 79 cases of fetal malformation,the rate was 2.0%,Which constitute the nervous system abnormalities accounted for the highest proportion（35.4%）,followed by circulatory system and limb bones,representing the proportions of 22.7% and 20.3%,respectively;Risk factors significantly associated with congenital malformations children include：perinatal sex,maternal age,smoking and alcohol consumption during pregnancy exposure and other factors,the difference was statistically significant（P〈0.05）;but pregnant women ethnic situation and children with congenital malformations was no correlation between the occurrence of the difference was not statistically significant（P〈0.05）. Conclusion：monitoring well children with congenital malformations,raise eugenic counseling and prenatal screening and diagnosis level,focusing on screening people with risk factors,to take appropriate and effective preventive measures to reduce the incidence of congenital malformations children,improve our quality of births.
出处
《中国优生与遗传杂志》
2016年第5期104-105,共2页
Chinese Journal of Birth Health & Heredity
关键词
先天性畸形儿
危险因素
预防措施
Congenital malformations children
Risk factors
Preventive measures
