摘要
目的回顾性分析超声BI-RADS 3级的乳腺结节（Φ≤2 cm）70例,探讨BI-RADS 3级的乳腺结节需临床干预的危险因素,以期提高临床诊治水平。方法选取2011年6月-2013年12月在新疆医科大学第五附属医院70例经超声首次分级为BI-RADS 3级的乳腺结节（Φ≤2 cm）进行回顾性分析。结果 70例病例中,恶性3例（4.29%）,良性病变67例（95.71%）;其中年龄（χ^2=5.011,P=0.027）、绝经（χ^2=9.240,P=0.004）、结节数目≥2（χ^2=7.624,P=0.010）、外上象限（χ^2=8.182,P=0.007）、有乳腺癌家族史（χ^2=7.222,P=0.013）、既往有乳腺良性肿瘤史（χ^2=9.892,P=0.003）、初潮年龄≤13岁（χ^2=9.736,P=0.003）、未生育（χ^2=8.182,P=0.007）与疾病进展密切相关;与雌激素水平及体重指数（BMI）无明显相关性。结论患者年龄、绝经、单发结节、位于外上象限、有乳腺癌家族史、既往有乳腺良性肿瘤史、初潮年龄以及未育与乳腺疾病进展密切相关,对于存在以上高危因素的BI-RADS 3级患者需进行临床干预,必要时手术治疗,不建议患者随访观察以免加重疾病进程。
Objective To retrospectively analyze 70 case with breast nodules（Φ≤2 cm） of ultrasonic BI-RADS category 3,and explore the risk factors for clinical intervention in order to improve the level of clinical diagnosis and treatment.Methods A retrospective analysis was performed for 70 patients with breast nodules（Φ ≤2 cm） of BI-RADS categories 3 who underwent the first ultrasound examination in the Fifth Affiliated Hospital of Xinjiang Medical University between June 2011 and December 2013.Results Of the 70 breast nodules,3（4.29%） were malignant and 67（95.71%） were benign.The age（χ~2= 5.011,P = 0.027）,menopause（χ~2= 9.240,P = 0.004）,the number of nodules（χ~2= 7.624,P = 0.010）,the upper outer quadrant（χ~2= 8.182,P = 0.007）,family history of breast cancer（χ~2= 7.222,P = 0.013）,history of benign breast disease（χ~2= 9.892,P = 0.003）,the menarche age（χ~2=9.736,P = 0.003） and no birth（χ~2= 8.182,P= 0.007） were closely related to disease progression; but not correlated with estrogen level or BMI index.Conclusions Age,menopause,single nodule,location in the outer upper quadrant,family history of breast cancer,history of benign breast disease,the menarche age and no birth are closely associated with breast disease progression.Patients with breast nodules of BI-RADS 3 who have the above risk factors should take clinical intervention; if necessary,surgical treatment.Follow-up observation is not recommended for the patients to avoid aggravating the disease process.
出处
《中国现代医学杂志》
CAS
北大核心
2016年第10期80-83,共4页
China Journal of Modern Medicine
