摘要
目的探讨早期血乳酸水平及乳酸清除率在住院患者发生心脏骤停后综合征（PCAS）中的变化和意义。方法将纳入研究的87例患者依据是否康复出院分为成活组（26例）和死亡组（61例），对两组早期血乳酸水平、乳酸清除率等临床资料进行统计学分析。结果成活组6h血乳酸值、血乳酸清除率、剩余碱、静脉血氧饱和度（Sev02）、APACHEⅢ评分分别为（8．46±2．37）mmol／L、（34．53±14．75）％、（-3．08±3．68）mmol／L、（68．35±6．33）％、（19．64±2．48）分，死亡组6h血乳酸值、血乳酸清除率、剩余碱、Sev02、APACHEⅢ评分分别为（12．32±3．56）mmol/L、（27．71±11．38）％、（-5．61±4．14）mmol／L、（63．22±5．94）％、（24．32±5．33）分，两组差异均有统计学意义（t=5．99、2．36、2．73、3．66、5．62，均P〈0．05）；6h血乳酸清除率、SevO2（％）、APACHEⅢ评分为影响PCAS预后的独立危险因素（OR=1．23、1．64、1．28，均P〈0．05）。结论早期血乳酸清除率可作评估PCAS预后的敏感指标，临床应充分重视。
Objective To investigate the significance of early blood lactic acid and lactic acid clearance in patients with post-cardiac arrest syndrome（PCAS）. Methods 87 cases were divided into the survival group（26 cases） and the death group（61 cases）. The clinical data of two groups were analyzed statistically. Results The 6h blood lactate （8.46 ± 2.37） mmol/L,6h blood lactate clearance rate （ 34.53 ± 14.75 ） %, the residual alkali （ - 3.08 ± 3.68 ） mmol/L,6h SevO2 （68.35 ± 6.33 ） %, APACHE m score （ 19.64 ± 2.48 ） points in the survival group were significantly better than those of the death group [ blood lactic acid value （12.32 ± 3.56 ）mmol/L,6h blood lactate clearance rate （27.71 ± 11.38 ） %, the residual alkali （ - 5.61 ± 4.14 ）mol/L, 6h SevO2 （ 63.22 ± 5.94 ） %, APACHE Ⅲ score （ 24.32 ± 5.33 ） points ], with significant differences between two groups （ t = 5.99,2.36,2.73, 3.66,5.62, all P 〈 0.05 ）. The 6h blood lactate clearance rate ,6h SevO2 and APACHE Ⅲ score were independent risk factors for the prognosis of PCAS （ OR = 1.23,1.64,1.28, all P 〈 0. 05 ）. Conclusion The early blood lactate clearance rate can be used as a sensitive indicator for evaluating the prognosis of PCAS.
出处
《中国基层医药》
CAS
2016年第11期1703-1706,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
心脏骤停
心脏骤停综合征
乳酸
乳酸清除率
Cardiac arrest
Cardiac arrest syndrome
Lactic acid
Lactate clearance
