摘要
目的系统评价针灸治疗2型糖尿病(T2DM)的疗效和安全性。方法计算机检索相关文献,按照制定的标准筛选后,由2名研究者单独提取资料、交叉核对,将数据录入Rev Man5.2作统计分析。结果共纳入9个研究,共743例患者。Meta分析结果表明1比较治疗后的总有效率,单纯针灸或针药联合治疗高于对照组[OR=3.60,95%CI(2.11,6.13)],差异具有统计学意义(Z=4.71,P<0.00001)。2比较治疗后的空腹血糖(FPG),试验组血糖降低幅度明显大于对照组[WMD=-1.20,95%CI(-1.38,-1.02)],差异具有统计学意义(Z=12.88,P<0.00001)。3比较治疗后的餐后2 h血糖(P2h PG),试验组血糖降低幅度明显大于对照组[WMD=-1.27,95%CI(-1.47,-1.06)],差异具有统计学意义(Z=12.02,P<0.00001)。结论针灸或针药联合治疗T2DM的临床效果显著优于单纯的中药或西药治疗,且无毒副反应。
Objective To systematically assess the efficacy and safety of acupuncture in treating type 2 diabetes. Methods Related literature was retrieved with a computer. After the data were sifted out from the literature according to the established criteria, they were collected and crossly checked by two researchers independently. The data were input to Rev Man5.2 for statistical analysis. Results A total of ten studies were included with a total of 743 patients. The results of Meta analysis showed 1） Post-treatment total efficacy rate was higher in the acupuncture or combined acupuncture and medicine group than in the control group [OR=3.60, 95%CI（2.11,6.13）] and there was a statistically significant difference（Z=4.71,P〈0.00001）; 2） Post-treatment range of decrease in fasting blood glucose（FBG） was significantly higher in the experiment group than in the control group [WMD=-1.20,95%CI（-1.38,-1.02）] and there was a statistically significant difference（Z=12.88,P〈0.00001）; 3） Post-treatment range of decrease in 2-h postprandial blood glucose（2h PBG） was significantly higher in the experiment group than in the control group [WMD=-1.27, 95%CI（-1.47,-1.06）] and there was a statistically significant difference（Z=12.02,P〈0.00001）. Conclusion Clinically acupuncture or combined acupuncture and medicine is more effective than Chinese herbal medicine or Western medication alone in treating T2 DM and has no toxic and side effects.
出处
《上海针灸杂志》
2016年第5期618-622,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
湖北省教育科学"十二五"规划课题(2014B095)
关键词
糖尿病
2型
针灸疗法
META分析
随机对照试验
文献研究
Diabetes
type 2
Acupuncture therapy
Meta analysis
Randomized controlled trial
Literature study
