摘要
目的分析中青年人初治耐多药肺结核患者的CT表现,探讨其影像学特点。方法回顾性分析2013年1月至2014年12月本院经药敏试验证实的28例中青年人耐多药（观察组）及同期84例中青年人非耐药（对照组）肺结核患者的CT影像资料;运用统计学方法检验两组间影像表现差异。结果两组间具有统计学意义的CT表现：（1）观察组少于对照组：病灶内钙化（χ^25.60,P〈0.025）;（2）观察组多于对照组：肺毁损（χ^211.03,P〈0.005）、胸膜钙化（χ^216.85,P〈0.005）、脓气胸（χ^214.54,P﹤0.005）、支气管扩张（χ^28.82,P〈0.01）。两组间无统计学意义的CT表现（P〉0.05）：斑片灶（χ^20.39）、结节灶（χ^20.9）、斑条灶（χ^22.68）、播散灶（χ^20.63）、空洞分布（χ^20.018）、多发空洞（χ^20.59）、空洞内液平（χ^20.11）、胸腔积液（χ^21.96）、纵隔肺门淋巴结肿大（χ^22.09）、纵隔肺门淋巴结钙化（χ^20.72）。结论两组患者病灶内钙化的差异具有统计学意义（P〈0.025）;在肺毁损、胸膜钙化、脓气胸、支气管扩张的征象上差异具有显著统计学意义（P〈0.01）。在CT诊断肺结核时,除斑片、结节、斑条、播散灶及多发空洞、胸腔积液等结核征象外,如存在肺毁损、胸膜钙化、脓气胸、支气管扩张等征象,要高度怀疑为耐多药肺结核。
Objective To analyze the symptoms of young and middleaged about the new active MDRTB（ Multi-drug resistant tuberculosis） Patients＇ symptoms shown by CT（ computed tomography）,and to study the imaging features of these symptoms. Methods Retrospectively analyzing the CT image data of the 28 MDRTB Patients as observation group and 84 Non MDRTB Patients as control group in our hospital from January 2013 to December 2014,which have been confirmed by drug sensitive tests; testing the imaging differences between the two groups by statistical methods. Results 1. We can get some CT signs with statistical significance between the two groups.（ 1） Less Patients in observed Group suffer from calcification within the lesion than those in control group（ χ^2 5. 60,P ﹤ 0. 025）.（ 2） More Patients in observed Group suffer than those in control group： destruction of lung（ χ^2 11. 03,P ﹤ 0. 005）,Pleural calcification（ χ^2 16. 85,P ﹤ 0. 005）,Pus and Pneumothorax（ χ^2 14. 54,P ﹤ 0. 005）,bronchodilatation（ χ^2 8. 82,P ﹤ 0. 01）. 2. There also exist some CT signs without statistical significance between the two groups（ P ﹥ 0. 05）,such as Patch foci（ χ^2 0. 39）,nodules foci（ χ^2 0. 9）,focal spot（ χ^2 2. 68）,dissemination foci（ χ^2 0. 63）,void distribution（ χ^2 0. 018）,multiple voids（ χ^20. 59）,void internal liquid（ χ^2 0. 11）,Pleural effussion（ χ^2 1. 96）,mediastinal hilar lymph nodes（ χ^2 2. 09）,mediastinal hilar lymph node calcification（ χ^2 0. 72）. Conclusion According to the analysis of the CT images between the two groups,we can find that calcification within the lesion of the Non MDRTB Patients has statistical significance（ P ﹤0. 05）,and that there are statistically significant differences in the symptoms of the MDRTB Patients such as lung lesions,Pleural calcification,Pneumothorax and bronchial dilatation（ P ﹤ 0. 01）. When diagnosed by CT,a Patient should be highly suspected to have infected with MDRTB if he has
出处
《临床放射学杂志》
CSCD
北大核心
2016年第5期719-722,共4页
Journal of Clinical Radiology
关键词
中青年人初治肺结核
耐多药
体层摄影术
X线计算机
Young and middle-aged about the new active MDR-TB Patients
Multi-drug resistant
Tomography
X-ray computed
