摘要
目的观察多模式超前镇痛对腹腔镜胆囊切除术全麻恢复期及术后疼痛的影响。方法选择80例在全麻下接受腹腔镜胆囊切除术的患者,随机分成多模式超前镇痛组(M组,n=40)与对照组(C组,n=40)。M组在手术开始前接受氟比洛芬酯注射液(1 mg/kg)、盐酸羟考酮(0.1 mg/kg)静脉注射以及0.5%罗哌卡因腹壁腔镜路径浸润,C组在手术开始前不做上述处理。观察两组患者在全麻恢复期的血压、心率、拔管时间、清醒时间、疼痛程度、不良事件。结果与C组相比,M组患者在全麻恢复期血压及心率更加平稳(P<0.05),呛咳、躁动发生率更低(P<0.05),术后疼痛程度显著降低(P<0.05),两组患者的拔管时间、清醒时间无显著性差异(P>0.05)。结论多模式超前镇痛有助于保持腹腔镜胆囊切除术患者全麻恢复期血液动力学的稳定性,降低呛咳及躁动发生率,减轻术后疼痛。
Objective To observe the effect of a preemptive multimodal analgesic regimen on recovery period of general anesthesia and postoperative pain after laparoscopic cholecystectomy. Methods Eighty patients undergoing laparoscopic cholecystectomy under general anesthesia were randomly assigned into group M（ n = 40） in which patients would preoperatively receive procedures including intravenous flurbiprofen axetil（ 1 mg/kg）,intravenous oxycodone hydrochloride（ 0. 1 mg/kg） and laparoscopic abdomen pathway infiltration with 0. 5% ropivacaine and group C（ n = 40） in which patients would not preoperatively receive procedures mentioned above. Items in recovery period including blood pressure（ BP）,heart rate（ HR）,time to remove intubation（ RIT）,time to be conscious（ BCT）,pain intensity,events of bucking or emergence agitation and other adverse effects were observed. Results BP and HR in group M were more stable than those in group C（ P〈0. 05）. Incidence of bucking or emergence agitation in group M were lower than that in group C（ P〈0. 05）. Pain intensity in group M was significantly lower than that in group C（ P〈0. 05）. There was no significant difference in RIT or BCT between two groups（ P〉0. 05）. Conclusion Preemptive multimodal analgesia is helpful in maintaining the stability of hemodynamics,decreasing the incidence of bucking and emergence agitation,and reducing pain intensity in recovery period.
出处
《临床和实验医学杂志》
2016年第9期913-917,共5页
Journal of Clinical and Experimental Medicine
关键词
腹腔镜胆囊切除术
多模式超前镇痛
全麻恢复期性
术后疼痛
Laparoscopic cholecystectomy
Preemptive multimodal analgesia
Recovery period of general anesthesia
Postoperative pain
