摘要
目的探讨前列地尔治疗高龄糖尿病合并慢性肾脏病患者疗效和安全性。方法选择我院2013年11月-2015年8月收治的高龄糖尿病合并慢性肾脏病患者82例,根据计算机随机分组法,随机分成观察组和对照组,每组各41例。对照组采用常规治疗,观察组在常规治疗的基础上加用前列地尔治疗。比较两组患者的血尿素氮、血肌酐、24 h尿蛋白。结果观察组患者的血尿素氮、血肌酐、24 h尿蛋白均优于对照组（P〈0.05）。结论前列地尔治疗高龄糖尿病合并慢性肾脏病患者的疗效显著。
Objective To investigate the effect of alprostadil in the treatment of elderly diabetic patients and the efficacy and safety of chronic kidney disease. Methods 82 cases with diabetes mellitus and chronic kidney disease patients were chosen in our hospital from November 2013 to August 2015, according to the computer random grouping method, were randomly divided into observation group and control group, 41 cases in each group. The control group received routine treatment, the observation group in the conventional treatment plus alprostadil treatment. Comparing the two groups of patients with blood urea nitrogen, serum creatinine, 24 h urine protein. Results The observation group of patients with blood urea nitrogen, serum creatinine, 24 h urine protein was better than the control group（P〈0.05）. Conclusion The curative effect of alprostadil in the treatment of elderly diabetic patients with chronic kidney disease is significant, worthy of clinical popularization.
出处
《中国继续医学教育》
2016年第12期126-127,共2页
China Continuing Medical Education
关键词
前列地尔
高龄
糖尿病
慢性肾脏病
Alprostadil
Elderly
Diabetes mellitus
Chronic kidney disease
