摘要
目的探讨内镜黏膜下剥离术（ESD）治疗食管早癌的疗效及中长期预后。方法对江苏省人民医院消化科2010年4月至2015年6月行ESD治疗的56例食管早癌患者进行随访分析，其中黏膜内癌39例，黏膜下癌17例，2例伴有脉管内癌栓。统计患者ESD整块切除率、完全切除率及术后残留、复发、新发等情况。随访时间1～62个月，平均24．4个月。结果56例患者中整块切除52例（92．9％），完全切除49例（87．5％），追加手术4例。术后残留1例（1．8％），复发2例（3．6％），新发2例（3．6％），食管外第2原发癌（胃癌）2例。未追加手术7例，无复发。随访期间无死亡。结论ESD治疗食管早癌具有完全切除率高、残留率及复发率低等优点，中长期预后较好。
Objective To investigate the intermediate and long-term efficacy of endoscopic submucosal dissection （ESD） for early esophageal cancer（EEC）. Methods A total of 56 patients with EEC underwent ESD at Jiangsu Province People＇s Hospital between April 2010 and June 2015.Among the 56 cases, there were 39 cases of intramucosal cancer, 17 cases of submucosal cancer. Intravaseular cancer embolus was found in 2 patients.The en bloc and complete resection rates, the residual,local tumor recurrence and new occurrence rates of EEC after ESD were evaluated. The average follow-up time was 24. 4 months, ranging fl＇om 1 to 62 months. Results The en bloc and complete resection rates were 92.9%（52） and 87.5% （49） ,respectively. Four patients were treated by additional esophagectomy. The cases of residual lesions, local tumor recurrence,new occurrence and second primary extra-esophageal cancer （ gastric cancer） was 1 （1.8%） , 2 （3.6%） , 2 （3.6%） and 2 （3.6%） , respectively. No additional surgical operations were performed in the 7 patients or no recurrence was found, and there was no death during the follow-up period. Conclusion ESD has the advantage of high complete resection rate,low residual and local tumor recurrence rate in treatment of EEC, and the intermediate and long-term outcomes are satisfaclory.
出处
《中华消化内镜杂志》
北大核心
2016年第5期308-311,共4页
Chinese Journal of Digestive Endoscopy
关键词
随访研究
内镜黏膜下剥离术
食管肿瘤
Follow-up studies
Endoscopic submucosal dissection
Esophageal neoplasms
