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基于阴道镜成像探讨高级别宫颈上皮内瘤变局部病变分区与五脏证素的相关性 被引量:8

Correlation study between high-grade cervical intraepithelial neoplasia cervical lesion zoning under the colposcope and syndrome elements of five zang viscera
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摘要 目的:探讨高级别宫颈上皮内瘤变(HSIL)宫颈局部病变分区与五脏证素的相关性。方法:对93例确诊为HSIL患者进行中医四诊信息采集,并进行阴道镜检查,构建阴道镜中医望诊坐标,结合活检病理回报确定HSIL病变在宫颈的坐标方位。结果:五脏病位证素在37个坐标分布中差异有统计学意义(P=0.002),肝病变在第一轮第7象限,脾病变在第一轮第11象限,肾病变在宫颈管内,与其他脏证素的坐标分布差异有统计学意义(α≤0.008);五脏病位证素在四象限的分布差异有统计学意义(P=0.000121),肝病变在左上象限,脾病变在右上象限,肾病变在宫颈管内,与其他脏证素的象限分布有差异有统计学意义(α≤0.005);五脏病位证素在轮数分布差异有统计学意义(P=0.008),肝病变涉及2轮及以上,脾病变局限于第一轮,肾病变局限于宫颈管,与其他脏证素的轮数分布差异有统计学意义(α≤0.005)。结论:HSIL宫颈病变分区与五脏证素有关,病变的坐标、象限、轮数分布可用于HSIL望诊。 Objective:To study the correlation between high-grade cervical intraepithelial neoplasia(HSIL)cervical lesion zoning under the colposcope and syndrome elements of five zang viscera.Methods:Four diagnostic information of93 patients diagnosed with HSIL through the cervical pathological examination were collected,cervical lesions check using colposcopy and coordinates determination of the cervical lesions in HSIL were conducted.Results:Five zang viscera disease syndrome elements was statistically significant in 37 coordinate distribution(P=0.002).Liver involved in the seventh quadrant of the first round,splenic lesions in the eleventh quadrant of the first round,and nephropathy in the cervical canal,coordinate distribution was different compared with other viscera syndromes(α≤0.008).There was a significant distribution of five zang viscera syndrome elements in the four quadrants(P=0.000121).The hepatic lesions in the upper left quadrant,the splenic lesions in the right upper quadrant,nephropathy in the cervical canal,quadrant distribution syndromes were different compared with other viscera(α≤0.005).Five zang viscera syndrome elements of disease location round number distribution was statistically significant(P=0.008).Liver lesions involved 2 round and above,splenic lesions confined to the first round,renal lesions confined to the cervical canal,there are differences in the distribution of the number of rounds(α≤0.005).Conclusion:HSIL lesions is related with syndrome elements of five zang viscera,and the coordinates,quadrant,round number distribution of the lesions can be used for HSIL inspection.
作者 吴冬梅 龚婷婷 李灿东 WU Dong-mei;GONG Ting-ting;LI Can-dong(The Second People’s Hospital of Fujian Province,Fuzhou 350003,China;Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China)
出处 《中华中医药杂志》 CAS CSCD 北大核心 2019年第4期1355-1358,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 中国博士后科学基金特别资助项目(No.2014T70605) 国家自然科学基金青年项目(No.81202721) 福建省科技厅引导性项目(No.2015Y0022)~~
关键词 高级别宫颈上皮内瘤变 阴道镜 宫颈病变分区 五脏证素 High-grade cervical intraepithelial neoplasia Colposcopy Cervical lesion zoning Syndrome elements of five zang viscera
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