摘要
目的:探讨更有效的促宫颈成熟的方法,为逾期妊娠计划分娩提供有效、安全、方便的方法。方法:采用病例对照研究的方法。选取90例具有引产适应证的初产孕妇,且宫颈评分≤6分,随机分为缩宫素引产组(对照组A)、地诺前列酮栓引产组(对照组B)和宫颈扩张球囊组(研究组)各30例。比较3组促宫颈成熟效果、阴道分娩成功率、不良反应及用药至临产的时间。结果:研究组促宫颈成熟有效29例,水囊脱落1例;对照组A有效12例;对照组B有效27例,研究组和对照组B有效率均高于对照组A(P<0.05)。研究组阴道分娩成功23例,对照组A 11例,对照组B 22例,差异有统计学意义(P<0.01)。对照组B有2例发生宫缩过度刺激,取出药物后立即好转,新生儿轻度窒息(Apgar 7分)1例,重度窒息(Apgar 3分)1例,胎心率异常6例;研究组胎心率异常1例,无子宫过度刺激、强直收缩和新生儿窒息;对照组A新生儿窒息(Apgar 7分和Apgar 6分)2例、胎心率异常5例,3组差异均无统计学意义(P>0.05)。对照组A用药至临产时间均长于对照组B及研究组(P<0.05)。结论:宫颈扩张球囊促宫颈成熟效果与地诺前列酮栓相似,高于缩宫素,并具有温和、安全和并发症少等优点。
Objective： To invetigate the effective method in promoting cervical maturity for providing an effective,safe and convenient delivery approach in overdue gestation. Methods： Ninety pregnant women with induction properties and cervical score less than or equal to 6 points were randomly divided into oxytocin induced labor group（ control group A）,dinoprostone suppository induced labor group（ control group B） and cervical dilation balloon group（ study group） by a case-control study（ 30 cases each group）. The effects of cervical maturity,success rate of vaginal delivery,adverse reactions and duration time from using medicine to delivery between three groups were compared. Results： The effective promoting cervical maturity in 29 cases and water balloon off in 1 case of study group were found,12 cases in control group A and 27 cases in control group B were valid,and the effective rates in study group and control group B were higher than that in control group A（ P〈0. 05）. The vaginal delivery of 23 cases in study group,11 cases in control group A and22 cases in control group B were successful,the difference of which was statistically significant（ P〈0. 01））. The uterine hyperstimulation in 2 cases of control group B occured,who improved immediately after removing the drug. The neonatal asphyxia in 1case（ Apgar for 7 points） and severe asphyxia in 1 case（ Apgar for 3 points） and abnormal fetal heart rate in 6 cases were identified.The abnormal fetal heart rate in 1 case,and no uterine hyperstimulation,tetanic contraction and neonatal asphyxia in study group were identified. The neonatal asphyxia in 2 cases（ Apgar for 7 points and 6 points） and abnormal fetal heart rate in 5 cases were found in control group A,the differences of whose between 3 groups were not statistically significant（ P〉0. 05）. The duration time from using medicine to delivery in control group A was longer than that in control group B and study group（ P〈0. 05）. Conclusions： The effect of cervica
出处
《蚌埠医学院学报》
CAS
2016年第4期470-472,共3页
Journal of Bengbu Medical College
关键词
引产
逾期妊娠
地诺前列酮栓
宫颈扩张球囊
缩宫素
induced labor
overdue gestation
dinoprostone suppository
cervical dilatation balloon
oxytocin
