摘要1病例介绍患者,女,73岁。因"间断胸闷、胸痛3年,再发加重1周"于2014年8月27日收住我院。血压147/70 mm Hg(1 mm Hg=0.133 k Pa),心率59次·min^-1,神志清楚。有2型糖尿病史10年,平时口服阿卡波糖片、格列齐特缓释片,间断监测血糖。高血压病史10年,目前未服用药物。无吸烟饮酒史。
1Ostapowicz G, Fontana R J, Schiodt FV, et al. Results of a prospective study of acute liver failure at 17 tertiary care cen- ters in the United States[J]. Ann Intern Med, 2002, 137 (12) : 947 -954. 被引量:1
2Larrey D. Epidemiology and individual susceptibility to adverse drug reactions affecting the liver[J], Semin Liver Dis, 2002, 22 (2) 145 -155. 被引量:1
3. Lee WM, Squires RH Jr, Nyberg SL, et al. Acute liver fail- ure= Summary of a workshop [ J ]. Hepatology, 2008, 47 (4) = 1401 -1415. 被引量:1
4Lucena MI, Andrade R J, Kaplowitz N, et al. Phenotypic charac- terization of idiosyncratic drug -induced liver injury: the influ- ence of age and sex [ J ]. Hepatology, 2009, 49 ( 6 ) 2001 - 2009. 被引量:1
5Myers RP, Shaheen AA, Li B, et al. Impact of liver disease, alcohol abuse, and unintentional ingestions on the outcomes of acetaminophen overdose[ J]. Clin Gastroenterol Hepatol, 2008, 6(8) : 918 -925. 被引量:1
6Lammert C, Einarsson S, Saha C, et al. Relationship be-tween daily dose of oral medications and idiosyncratic drug - induced liver injury: search for signals [ J]. Hepatology, 2008, 47(6} : 2003 -2009. 被引量:1
7Daly AK, Donaldson PT, Bhatnagar P, et al. HLA - B 5701 genotype is a major determinant of drug -induced liver injury due to flucloxacillin[J]. Nat Genet, 2009, 41 (7} ; 816 -819. 被引量:1
8Daly AK, Day CP. Genetic association studies in drug -induced liver injury(J]. Semin Liver Dis, 2009, 29(4}: 400 -411. 被引量:1
9Navarro V. Hepatic adverse event nomenclature document (on- line}. Available from URL; http; //www. fda. gov/cder/liver- tox/presentations 2005/vic -Navarro. ppt. (accessed 5 Febru- ary 2009). 被引量:1
10Andrade R J, Lucena MI, Kaplowitz N, et al. Outcome of a- cute idiosyncratic drug -induced liver injury_. Long -term fol- low - up in a hepatotoxicity registry[ J ]. Hepatology, 2006, 44(6) .- 1581 -1588. 被引量:1