摘要
目的探究丙泊酚复合地佐辛靶控输注在妇科腔镜手术全身麻醉中的应用效果。方法选取我院2014年11月~2015年11月收治的行妇科腔镜手术全身麻醉患者共91例,随机分为对照组与观察组,对照组接受丙泊酚复合瑞芬太尼靶控输注,观察组接受丙泊酚复合地佐辛靶控输注。比较两组患者不同时间点血流动力学指标、麻醉效果及不良反应发生率。结果两组患者T0时MAP、HR、Sa O_2%及RR差异无统计学意义（P〉0.05）。观察组T1、T2、T3及T4时ΔMAP、ΔHR、ΔSa O_2%及ΔRR均明显低于对照组（P〈0.05）。观察组丙泊酚使用量为（413.1±18.4）mg、VAS评分为（3.15±0.35）,不良反应发生率为4.3%,均明显低于对照组（P〈0.05）。结论丙泊酚复合地佐辛靶控输注可有效稳定术中循环,减少丙泊酚使用量及降低不良反应发生率,镇痛效果好,值得临床推广应用。
Objective To explore the application effects of propofol combined with target-controlled infusion dezocine in gynecological laparoscopic surgery with general anesthesia. Methods 91 cases gynecological laparoscopic surgery with general anesthesia patients from November 2014 to November 2015 in our hospital were selected and were randomly divided into control group and observation group.Patients in control group were given propofol combined with target-controlled infusion remifentanil.Patients in observation group were given propofol combined with target-controlled infusion dezocine.The hemodynamic index,anesthesia effects and the incidence rate of adverse effects at different times between two groups were compared. Results The MAP,HR,Sa O_2% and RR at T0 between two groups had no obvious difference（P〈0.05）.The ΔMAP,ΔHR,ΔSa O_2% and ΔRR in observation group at T1,T2,T3 and T4were obvious lower than those in control group（P〈0.05）.The propofol usage amount,VAS score and incidence rate of adverse effects in observation group was respectively（413.1 ±18.4）mg,（3.15±0.35） and 4.3%,which was obvious lower than that in control group（P〈0.05）. Conclusion Propofol combined with target-controlled infusion dezocine can maintain the circulation stable effectively,decrease the usage amount of propofol, has less incidence rate of adverse effects and good analgesic effect.It is worth to popularize in clinic.
出处
《中国当代医药》
2016年第11期116-118,共3页
China Modern Medicine
关键词
丙泊酚
地佐辛
靶控输注
全身麻醉
妇科腔镜手术
Propofol
Dezocine
Target-controlled infusion
General anesthesia
Gynecological laparoscopic surgery
