摘要
目的了解茂名地区儿童9种呼吸道病原体的IgM抗体检测结果及流行情况。方法取6 241例初步诊断为吸道感染患者的血清,采用间接免疫荧光法同时检测9种病原体IgM抗体。9种非典型病原体分别是嗜肺军团菌(LP)、肺炎支原体(MP)、Q热立克次体(COX)、肺炎衣原体(CP)、腺病毒(ADV)、呼吸道合胞病毒(RSV)、甲、乙型流感病毒(INFA/B)和副流感病毒(PIVS)。结果共检测6 241份血清,其中1 320份阳性,非典型病原体感染阳性率为21%,其中MP(15.12%)感染率最高,其次为INFB、LP、ADV和PIVS,它们的感染率分别为3.03%、1.92%、0.54%和0.22%。感染率最小的病原群体为RSV、COX、INFA和CP,它们的感染率分别为0.14%、0.11%、0.048%和0.016%。结论茂名地区儿童急性呼吸道感染的病原体主要是MP,病原体检出率与季节有关。
Objective To investigate the infectious rates of 9common pathogens and epidemiology in children with acute respiratory tract infections（ARI）in Maoming district.Methods The serum were collected from 6 241 children with acute respiratory infection.IgM of 9common pathogen including Mycoplasma pneumoniae（MP）,Legionella pneumophila（LP）,Coxiella burnetii（C.burnetii）,Chlamydophila pneumoniae（CP）,adenovirus（ADV）,respiratory syncytial virus（RSV）,type A and type B influenza virus（INFA and INFB）,and parainfluenza virus（PIVS）,were detected using immunofluorescence assay.Results Among 6 241 cases,1 320 showed atypical pathogens infection,and infection rate was 21%.The positive rate of MP was 15.12%,the highest infectious pathogen;followed by the positive rate of INFB,LP,ADV and PIVS were 3.03%,1.92%,0.54% and 0.22% respectively.The pathogens with the lowest positive rate were RSV,COX,INFA and CP,their infectious rates were 0.14%,0.11%,0.048%and 0.016% respectively.Conclusion The infection rate of atypical pathogen among children is high in this area,which should be taken seriously.MP is the most common pathogen in children with ARI in Maoming district.The pathogen positive rate has relationship with season.
出处
《国际检验医学杂志》
CAS
2016年第9期1226-1227,共2页
International Journal of Laboratory Medicine
关键词
呼吸道感染
病原体
间接免疫荧光法
IGM抗体
respiratory infection
pathogens
indirect immunofluorescence
IgM antibody
