摘要
目的探讨复方丹参滴丸联合舒洛地特软胶囊治疗糖尿病肾病Ⅳ期的临床疗效。方法将60例糖尿病肾病Ⅳ期患者随机分成观察组(30例)和对照组(30例),对照组患者采用舒洛地特软胶囊治疗。观察组采用复方丹参滴丸联合舒洛地特软胶囊治疗。观察两组患者治疗前后的肾功能指标及血脂指标改善及临床疗效。结果治疗3个月后,观察组显效率和总有效率均显著高于对照组(P<0.05),观察组患者治疗后24h UAlb、β2-MG、UAER及BUN等肾功能指标显著低于对照组(P<0.05),观察组治疗后TC、TG、LDL-C、HDL-C等血脂指标改善显著优于对照组(P<0.05)。结论复方丹参滴丸和舒洛地特软胶囊联合治疗Ⅳ期DN能降低尿微量白蛋白,改善肾功能,延缓肾功能衰竭。
Objective To integrative clinical efficacy of compound Danshen dropping pills combined with sulodexide soft capsules in treatment of diabetic nephropathy Ⅳ. Methods 60 patients with diabetic nephropathy Ⅳ were randomly divided into observation group（30 cases）and control group（30 cases）. Patients in control group were treated by sulodexide soft capsules, while others were treated by compound Danshen dropping pills combined with sulodexide soft capsules. Renal function and blood fat indexes, clinical efficacy were compared between two groups. Results At 3nd month after the treatment, the rate of efficiency and total efficiency in observation group were significantly higher than those in control group（P〈0.05）; The level of 24 h UAlb, β2-MG, UAER, BUN in the observation group were significantly lower than those in the control group（P〈0.05）; the level of TC, TG, LDL-C and HDL-C in the observation group were significantly improved than those in the control group（P〈0.05）. Conclusion The treatment of compound Danshen dropping pills combined with sulodexide soft capsules for diabetic nephropathy Ⅳ can reduce urinary albumin, improve renal function and delay renal failure.
出处
《中国医药科学》
2016年第7期102-104,共3页
China Medicine And Pharmacy
关键词
复方丹参滴丸
舒洛地特软胶囊
糖尿病肾病
Compound Danshen dropping pills
Sulodexide soft capsules
Diabetic nephropathy
