摘要
目的:了解住院患者尿培养中分离的病原菌分布及耐药状况,为尿液感染性疾病的诊断、治疗提供用药依据。方法:对有尿路感染症状尿液培养出细菌的229例患者进行尿液细菌培养鉴定及药敏实验,并对细菌的耐药进行统计分析。结果:尿路感染致病菌以革兰阴性杆菌(190株)为主(82.9%),分列前3位的是大肠埃希菌(72.6%)、铜绿假单胞菌(7.9%)、肺炎克雷伯菌(4.7%);革兰阳性球菌(39株)以粪肠球(31.7%)和屎肠球菌(46.2%)为主,革兰阴性杆菌对头孢哌酮/舒巴坦、哌拉西林舒巴坦、阿米卡星敏感性较高,而对左氧氟沙星、头孢曲松耐药性较高。革兰阳性球菌对万古霉素、替考拉宁、利奈唑胺敏感性较高,对红霉素、四环素、利福平耐药性较高。结论:革兰阴性杆菌为尿路感染的主要致病菌,治疗预防应选用酶抑制剂等耐药性低的药物,临床合理选用抗菌药具有重要意义。
Objective:To investigate distribution and resistance of pathogens in inpatients with urinary culture,to provide the reference for the clinical effective diagnosis and treatment of urinary tract infection.Methods:The bacteria identification and drug sensitivity of inpatients with urinary tract infection were tested and the data of drug resistance of bacteria were analyzed.Results:Pathogens in inpatients with urinary culture were mainly gram negative bacteria(190 strains,82.9%),the first 3 were Escherichia coli(72.6%),Pseudomonas aeruginosa(7.9%),Klebsiella pneumoniae(4.7%).Gram-positive coccus(39 strains)were Enterococcus faecalis(31.7%) and Enterococcus faecium(46.2%).Drug sensitivity of Cefoperazone/Shubatan, piperacillin sulbactam and amikacin were high for gram negative bacteria,but levofloxacin and ceftriaxone were low.Drug sensitivity of vancomycin,linezolid,teicoplanin were high for gram-positive coccus,but erythromycin, tetracycline, rifampin were low.Conclusions:Knowing the primary pathogens of urinary tract infection and enzyme inhibitor in the low resistance drug is of great significance to guide the clinical rational use of antimicrobial drugs.
出处
《安徽卫生职业技术学院学报》
2016年第2期137-138,共2页
Journal of Anhui Health Vocational & Technical College
基金
合肥市第三人民医院科研课题(编号:院科合同2015(21)号)
关键词
尿路感染
细菌分布
耐药性
Urinary tract infection
Pathogen
Drug resistance
