摘要
目的观察中西医结合分期治疗儿童肺炎支原体感染咳嗽的临床疗效。方法江西中医药大学附属医院儿科门诊2013年3月至2014年12月收治肺炎支原体感染咳嗽患儿120例,随机分为中医治疗组、西医治疗组及中西医治疗组各40例。中医治疗组给予中医分期治疗。初期以解表驱邪、清热化痰,或和解少阳为法,治疗1个疗程;中期以理气化痰、活血化瘀,佐以清热解毒为法,治疗1个疗程;恢复期以补益气阴,调和营卫,清除余邪为法,治疗2个疗程。西医治疗组给予口服阿奇霉素干混悬剂治疗,服用3d,停4d。中西医治疗组在西医治疗基础上加用中医分期治疗。3组患儿均以7d为1个疗程,共治疗4个疗程,治疗后随访2个月。观察3组治疗7、14、28d后咳嗽、咳痰症状积分,主症、次症积分的改善情况;观察治疗后及随访2个月后MP-IgM转阴率;观察3组临床疗效。结果 (1)治疗前后疗效比较:治疗7d后,中西医治疗组总有效率高于中医治疗组、西医治疗组,差异有统计学意义(P<0.017),中医治疗组与西医治疗组总有效率比较差异无统计学意义(P>0.017)。治疗14d后,中西医治疗组总有效率高于西医治疗组,差异有统计学意义(P<0.017);中医治疗组总有效率与西医治疗组、中西医治疗组比较差异无统计学意义(P>0.017)。治疗28d后,3组疗效比较差异无统计学意义(P>0.05)。(2)MP-IgM转阴率比较:治疗后3组MP-IgM转阴率比较差异无统计学意义(P>0.05)。随访2个月后3组MP-IgM转阴率比较差异有统计学意义(P<0.05),中西医治疗组MP-IgM转阴率明显高于中医治疗组及西医治疗组,差异有统计学意义(P<0.017),而中医治疗组与西医治疗组MP-IgM转阴率比较差异无统计学意义(P>0.017)。结论在西医阿奇霉素治疗的基础上加用中医分期疗法治疗儿童肺炎支原体感染咳嗽在改善临床症状和体征方面,治疗有效,且明显优于单纯中医分期治疗及单纯阿�
Objective To observe the clinical effect of the treatment for pediatric Mycoplasma pneumoniae infection cough by integrated medicine staging therapies.Methods Select 120 cases of children with Mycoplasma pneumoniae infection and they were divided into Chinese medicine treatment group（group A）,Western medicine treatment group（group B）,and the combination therapy group（group C）,40 patients in each group.Group A received Chinese medicine for the staging treatment;group B was given azithromycin therapy;group C was given azithromycin combined with Chinese medicine staging therapy.Three groups of children had a treatment course of 7days,totally four courses of treatment,and then were followed up for two months after treatment.After 7days,14 days and 28 days of treatment,respectively,observe the cough and expectoration scores,the improvement in major and minor symptom scores;observe the negative-conversion rate of MP-IgM after treatment and at 2months of follow-up;observe the clinical effect in the 3groups.Results（1）Comparison of the effect before and after treatment：after 7dof treatment,the total effective rate of Group C was higher than that of Group A and B,the difference being statistical（P〈0.017）,but there was no statistical difference between Group B and C（P〈0.017）;after 14 dof treatment,the total effective rate of Group C was higher than that of Group C（P〈0.017）,but there was no statistical difference between Group A and Group B and C（P〈0.017）.After 28 dof treatment,there was no statistical difference in the effect among the 3groups（P〈0.05）.（2）Comparison of negative-conversion rate of MP-IgM：there was no statistical difference among the 3groups after treatment（P〈0.05）;at 2months of follow-up,the difference in the rate was statistical among the 3groups（P〈0.05）,which was higher in Group C（P〈0.017）,but no statistical difference was shown between Group A and B（P〈0.017）.Conclusion In terms of improving clinical symptoms and signs,the treatme
出处
《中国中西医结合儿科学》
2016年第2期139-143,共5页
Chinese Pediatrics of Integrated Traditional and Western Medicine
关键词
肺炎支原体感染
咳嗽
中西医结合治疗
儿童
Mycoplasma pneumoniae infection
Cough
Integrative Chinese and western medicine treatment
Children
