摘要
目的评价Z形自膨式金属支架(Z—SEMS)在节段性下腔静脉型Budd—Chiari综合征(BCS)介入治疗中的应用及中长期随访结果。方法回顾性分析2004年8月至2014年12月接受Z—SEMS支架治疗的41例节段性下腔静脉型BCS患者临床资料.并收集术后累计1、2、2~5、5~10年随访数据。结果41例患者均成功接受经皮球囊血管成形术(PTBA)和Z-SEMS支架植入术.术后患者下腔静脉高压症状明显改善,显效35例(85.4%),有效6例(14.6%),总有效率100%。4例患者(9.8%)出现支架移位并发症。所有患者获随访1~125个月.平均(64.12±41.48)个月,1例患者术后4个月出现门静脉高压症状,作经颈内静脉途径门腔分流术后缓解,4例新发肝细胞癌,5例死亡。4例(9.8%)支架再阻塞,再次PTBA术恢复通畅。累计1、2、2~5、5~10年下腔静脉一次通畅率分别为95.1%(39/41)、94.1%(32/34)、90.3%(28/31)、83.3%(20,24),二次通畅率分别为100%(41/41)、100%(34/34)、100%(31/31)、100%(24/24)。结论Z-SEMS支架治疗节段性下腔静脉BCS安全有效,再阻塞率低,中长期疗效满意。术后应注意随访支架及新发肝细胞癌。
Objective To discuss the application of percutaneous Z-expandable metallic stent (Z- EMS) implantation in treating segmental inferior vena cava type Budd-Chiari syndrome (BCS) and to analyze its mid-to-long-term results. Methods The clinical data of 41 consecutive BCS patients with segmental obstruction of inferior vena cava (SOIVC), who were admitted to authors' hospital to receive percutaneous Z- EMS implantation during the period from August 2004 to December 2014, were retrospectively analyzed. The cumulative follow-up data of one, 2, 2-5 and 5-10 years were collected. Results Both pereutaneous transluminal balloon angioplasty (PTBA) and Z-EMSimplantation were successful accomplished in all 41 patients. After the treatment, the symptoms of inferior vena cava (IVC) hypertension were obviously improved; significant response was achieved in 35 patients (85.4%) and curative effect in 6 patients (14.6%), the total effect rate being 100%. Stent migration occurred in 4 patients (9.8%). All patients were followed up for 1-125 months, with a mean of (64.12±41.48) months. One patient developed IVC hypertension at 4 months after treatment, which was relieved after receiving transjugular intrahepatic portosystemic stent shunting; 4 patients developed hepatocellular carcinoma (HCC) and 5 patients died. Re-obstruction of the stent was seen in 4 patients and the stent returned to patent after receiving PTBA. The cumulative primary patency rates of IVC at one, 2, 2-5 and 5-10 years were 95.1% (39/41), 94.1% (32/34), 90.3% (28/31) and 83.3% (20/24)respectively, while the secondary patency rates of IVC at one, 2, 2-5 and 5-10 years were 100% (41/41), 100% (34/34), 100% (31/31) and 100% (24/24) respectively. Conclusion For the treatment of segmental inferior vena cava type Budd-Chiari syndrome, Z-EMS implantation is safe and effective, its re-occlusion rate is lower and its mid-to-long-term result is satisfactory. Follow-up observation should be focused o
出处
《介入放射学杂志》
CSCD
北大核心
2016年第5期391-395,共5页
Journal of Interventional Radiology