摘要
目的探讨连续性肾脏替代治疗（CRRT）开始时机对合并急性肾损伤（AKI）重症患者生存率及肾功能恢复率的影响。方法选择我院2012年1月至2015年1月采用CRRT的合并AKI重症患者200例，根据开始行CRRT时所属AKI时期将患者分为1期（A组）、2期（B组）和3期（C组），比较3组患者的存活率及生存者肾功能恢复率。结果经过治疗后，A、B、C组肾功能恢复率、存活率、病死率比较差异均有统计学意义[91．04％、52．11％与29．03％，92．5％、73．6％与36．2％，7．5％、26．2％与63．8；χ2值分别为6．266、16．143、16．143，P均〈0．05]，且A组患者治疗后肾功能恢复率、存活率均显著高于B组、C组，差异均有统计学意义（P均〈0．05）；A、B、C组患者治疗后肾功能指标较治疗前均有显著提高，差异均有统计学意义（P均〈0．05）。结论合并急性肾损伤重症患者早期进行CRRT治疗可显著提高患者生存率，有利于患者肾功能的恢复。
Objective To investigate the influence of start time of continuous renal replacement therapy （CRRT） on the survivay and renal function recovery of patients with severe acute kidney injury （AKI） Methods Two hundred cases of severe AKI patients in the Traffic Hospital of Shandong Province from January 2011 to January 2014 were selected and divide into groups A of 1 phase,group B of 2 phase and group C of 3 phase based on the CRRT starting time. The survivary and renal function recovery of 3 groups patients were compared. Results After treatment, the recovery rate of renal function, survival rate and mortality of patients in group A were 91.04%, 92. 5% and 36. 2%, significantly higher than that of group B （ 52. 11%, 73.6% and 7. 5% ） and group C （ 29.03%, 36. 2% and 63.8% ） , the differences were statistically significant （ χ2 = 6. 266, 16. 143,16. 143;P〈0.05） ;and the recovery rate of renal function and survival rate of group A was higher than of group B and C （P〈0.05） ;and renal function index of groupA, B, C all significantly improved than before treatment,there were statistically significant differences （ P 〈 0, 05 ） . Conclusion Early CRRT treatment can significantly improve the survival rate of patients with SCKI, which would be good for patients to recover renal function.
出处
《中国综合临床》
2016年第4期335-338,共4页
Clinical Medicine of China
