摘要
目的探讨综合疗法对不同年龄段、不同弱视程度、不同屈光性质及不同注视性质的弱视儿童的治疗效果。方法选取2013年8月至2015年8月在新疆民政康复医院治疗的弱视患儿620例（891眼）,采用激光弱视治疗仪、遮盖疗法、精细作业疗法、同视功能训练及三维立体训练等方法综合治疗。以40 d为一个大疗程,每治疗10 d休息1-2 d。疗效按照基本治愈、有效和无效分为三组。采用眼数和百分比的方式描述数据。患者的弱视程度、年龄二项指标与疗效的相关性,采用精确概率法进行检验,并计算pearson相关系数r;患者的屈光性质、注视性质二项指标与疗效的比较,采用Kruskal Wallis秩和检验。结果 620例患儿（891只眼）中,基本治愈者824只眼,占92.48%;有效者59只眼,占6.62%;无效者8只眼,占0.89%,总有效率为99.10%。远视性质、近视性质、混合散光、屈光参差、斜视性弱视、中心注视及旁中心注视等患者的治疗有效率分别为99.6%、99.4%、100%、96.7%、93.6%、99.7%及97.8%。全部患者按照弱视程度分为轻度、中度和重度。轻度弱视者580只眼全部治愈,治愈率为100.0%;中度弱视者中基本治愈、有效及无效的分别为218只眼、45只眼及3只眼,分别占82.0%、16.9%及1.1%。重度弱视者中基本治愈、有效及无效的分别为26只眼、14只眼及5只眼,分别占57.8%、31.1%及11.1%。弱视程度和疗效之间存在着相关性（Fisher确切概率P〈0.001）,并且随着弱视程度的升高,疗效逐渐降低（Pearson系数r=0.430,P〈0.001）。全部患者按照年龄3-6岁、7-10岁和11-14岁分为三组。3-6岁组112只眼中,基本治愈和治疗有效的分别为108只眼和4只眼,分别占96.4%和3.6%;7-10岁组中基本治愈、有效和无效的分别为394只眼、20只眼和3只眼,分别占94.5%、4.8%和0.7%;11-14岁组中,基本治愈、有效和无效的分别为322只眼、35只眼和5只眼,分别占89.0%、9.7%和1.3%。�
Objective This study is to investigate the therapeutic effects of combination therapy on amblyopic children with different ages,amblyopia degrees,and refractive and fixation properties.Methods 620 patients（ 891 eyes） with amblyopia children in Xinjiang Civil Affairs Rehabilitation Hospital treatment from August 2013 to August 2015 were selected. These amblyopic children were subjected to the combination therapy with laser treatment,occlusion therapy,fine occupational therapy,visual function training,and three-dimensional training. A treatment course consisted of 40 d,during which rest（ 1-2 d） was taken every 10 d. The curative effect was divided into three groups according to the basic cure,effective and ineffective. Data is described by means of eye numbers and percentages. Correlation with the degree of amblyopia,age two parameters and effect,the exact probability test,and calculate the Pearson correlation coefficient r; patients with refractive properties,look at the properties of two indexes and curative effect comparison,using the Kruskal Wallis rank sum test. Results In these 891 amblyopic eyes subjected to the combination therapy,there were 824 cases of basic cure（ 92. 48%）,59 cases of effective treatment（ 6. 62%）,8 cases of ineffective treatment（ 0. 89%）,with a total effective rate of 99. 10%. The therapeutic effective rates for amblyopic children with hyperopia,myopia,mixed astigmatism,anisometropia,strabismus,central fixation,and eccentric fixation were 99. 6%,99. 4%,100%,96. 7%,93. 6%,99. 7%,and 97. 8%respectively. All patients were divided into mild,moderate and severe according to the degree of amblyopia.Mild amblyopia 580 eyes cured,the cure rate was 100. 0%; moderate amblyopia cure,the effective and ineffective respectively 218 eyes,45 eyes and 3 eyes,accounted for 82. 0% and 16. 9% and 1. 1%. The basic cure,effective and ineffective were 26 eyes,14 eyes and 5 eyes respectively,accounting for 57. 8%,31. 1%and 11. 1% respectively. There was a correlation between the degree of amb
出处
《中华眼科医学杂志（电子版）》
2016年第2期75-80,共6页
Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
基金
新疆自治区自然科学基金(No.20151008773)
关键词
弱视
儿童
综合治疗
疗效评价
Amblyopia
Children
Combination therapy
Treatment efficiency
