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甲状腺乳头状癌中BRAF^(V600E)基因突变与临床病理特征的关系 被引量:3

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摘要 在我国,甲状腺癌的发病率明显上升,甲状腺乳头状癌(papillary thyroid carcinoma,PTC)是甲状腺癌中最常见的类型,占60%-80%-[1]。PTC大部分预后良好,10年生存率可达80%-90%,总体致死率低〈10%-[2],但仍有〈10%患者术后因肿瘤复发或转移而预后变差。预测甲状腺癌手术后的危险评价系统是基于患者的临床病理特征,包括年龄、性别、肿瘤大小、单发还是多发、
出处 《山西医药杂志》 CAS 2016年第8期928-930,共3页 Shanxi Medical Journal
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参考文献6

  • 1吴恢升,何劲松,陈伟财,王先明.选择性颈淋巴结清除术在乳头状甲状腺癌手术治疗的临床应用[J].中国普通外科杂志,2012,21(5):532-535. 被引量:17
  • 2Wan PT,Garnett MJ,Roe SM,et al.Mechanism of activation of the RAF-ERK signaling path way by oncogenic mutation of BRAF[J].Cell,2004,116(6):855-867. 被引量:1
  • 3Li C,Lee KC,Schneider EB,et al.BRAFV600Emutation anits association withclinicopathological features of papillathyroid cancer meta analysis[J].J Clin Endocrinol Meta,2012,97:4559-4570. 被引量:1
  • 4Kim TY,Kim WB,Song JY,et al.The BRAF mutation is not associated with prognostic factors in Korean patientswith conventional papillary microcarcinomas[J].Clin Endocrinol(Oxf),2005,63(5):588-593. 被引量:1
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  • 6Xing M.Prognosticutility of BRAf mutation in papillary thyroid cancer[J].Mol Cell Endocrnol,2010,32:11-86. 被引量:1

二级参考文献15

  • 1李树玲.我国甲状腺癌外科现状与展望[J].临床外科杂志,2006,14(3):129-130. 被引量:46
  • 2Palazzo FF, Gosnell J, Savio R. Lymphadenectomy for papillarythyroid cancer: changes in practice over four decades[J]. Eur J Surg Oncol, 2006, 32(3):340-344. 被引量:1
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  • 4Robbins KT, Clayman G, Levine PA, et al. Neck dissection classification updates: revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology- Head and Neck Surgery[J]. Arch Otolaryngol Head Neck Surg, 2002, 128(7):751-758. 被引量:1
  • 5Guideline of thyroid cancer:in clinical practice guidelines in oncology,version 1, 2010, National Comprehensive Cancer Network (NCCN). 被引量:1
  • 6Guidelines for the management of thyroid cancer in adults.2007. British Thyroid Association and Royal College of Physicians,London. 被引量:1
  • 7Caron NR, Tan YY, Ogilivie JB, et al. Selective modified radical neck dissection for papillary thyroid cancer-is level I, II and V dissection always necessary?[J]. World J Surg, 2006, 30(5):833- 840. 被引量:1
  • 8Kupferman ME, Weinstock YE, Santillan AA, et al. Predictors of level V metastasis in well-differentiated thyroid cancer[J].Head Neck, 2008, 30(11):1469-1474. 被引量:1
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  • 10刘春萍,明洁,石岚,李治,黄韬.分化型甲状腺癌手术治疗方法的探讨[J].中国普通外科杂志,2008,17(5):409-411. 被引量:48

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