摘要
术后肿瘤复发是导致患者死亡的主要原因。大量研究表明:围手术期患者的免疫功能与肿瘤复发密切相关,而麻醉药物或方法对机体免疫功能的抑制是导致肿瘤复发的重要因素。因此,本文拟就麻醉药物或方法对围手术期免疫功能和肿瘤复发的影响进行综述。
Most cancer-related deaths in patients who have received previous surgical treatment are caused by tumor recurrence. Considerable numbers of studies have shown that immune function in perioperative period is closely related to tumor recurrence of patients underwent curative resection. Meanwhile, retrospective studies suggest some anesthetics or anesthetic techniques may lead to tumor recurrence as a result of its perioperative immunosuppression. Therefore, this article is intended to summarize the effects of anesthetic drugs or techniques on perioperative immune function and tumor recurrence.
出处
《生命的化学》
CAS
CSCD
2016年第2期213-218,共6页
Chemistry of Life
基金
国家自然科学基金项目(81371251)
湖北省自然科学基金项目(2014CFB416)
关键词
麻醉
围手术期
免疫抑制
肿瘤复发
影响
anesthesia
perioperative period
immunosuppression
tumor recurrence
effect