摘要
目的建立健肾Ⅰ号胶囊质量控制方法。方法采用薄层色谱法对健肾Ⅰ号胶囊中龙葵、地榆、忍冬藤和乌药进行定性鉴别,HPLC法同时测定健肾Ⅰ号胶囊中没食子酸、红景天苷、绿原酸和咖啡酸的含量。结果薄层色谱鉴别斑点清晰,阴性对照无干扰;没食子酸、红景天苷、绿原酸、咖啡酸平均加样回收率分别为98.72%、97.45%、97.57%和97.13%,RSD分别为0.97%、1.36%、1.49%和2.18%。结论质量控制方法简便、准确、专属性强,可用于该制剂的质量控制。
Objective To establish quality control method for Jianshen CapsulesⅠ（JCⅠ）. Methods Solanum nigrum L.,Sanguisorba officinalis L.,Lonicera japoraca Thunb. and Lindera aggregata Kosterm. in JCⅠ were identified by thin layer chromatagraphy（TLC）,the contents of gallic acid,alidroside,chlorogenic acid and caffeic acid were determined by HPLC. Results TLC Identification spots were fairly clear and the blank test showed no interference. The average recovery of gallic acid,alidroside,chlorogenic acid and caffeic acid was 98.72%,97.45%,97.57%,and 97.13%,and RSD was 0.97%,1.36%,1.49% and 2.18%,respectively. Conclusion The established quality control method is simple,special,reproducible and can be used for quality control of JCⅠ.
出处
《国际药学研究杂志》
CAS
CSCD
北大核心
2016年第2期355-358,共4页
Journal of International Pharmaceutical Research
