摘要
目的探索应用ReCell试剂盒辅助自体表皮细胞移植治疗继发性色素性病变的临床效果。方法对12例继发性色素性病变患者应用自体表皮细胞移植技术治疗。选择适当的供区，按照供区和受区1：40或1：80的比例切取厚度为0．2mm的刃厚皮片，经ReCell试剂盒酶解后，形成表皮细胞悬液。病变部位应用微型动力系统磨削后，创面喷洒制备的表皮细胞悬液，术后加压包扎。应用温哥华瘢痕评分表评判最终病变改善程度。结果平均随访（13±6）个月。11例患者病变明显改变，1例患者病变改善不明显。结论应用ReCell试剂盒辅助的自体表皮细胞移植是治疗继发性色素性病变的有效方法之一，操作简便、快速，损伤小、安全。
Objective To evaluate the primarily therapeutic outcomes of a new autologous cell transplantation technique, or namely ReCell technique, for acquired disorders of pigmentation. Methods Twelve patients with acquired disorders of pigmentation were treated with ReCell tech- nique in recent 3 years. During the procedure, a small area skin biopsy was harvested from a healthy nearby zone. It was then processed through the ReCell kit and small amount of cell suspension was obtained. After dermal brasion of the disorder area of pigmentation, the suspension was sprayed to the raw wound and nonadherent dressings were used for temporally coverage. The lesional improvement was finally evaluated with Vancouver scar scale. Results With a mean follow-up of 13＋_6 months, 11 cases were significant il improved but I case was insignificant; there was no major complication oc- curred except one hematoma. Patient＇s self-reported data analysis revealed there was statistically signif- icant improvement regarding the appearance of the treated area. The analysis of surgeon＇s evaluation scale data also reached the same conclusion. Conclusions ReCell technique can improve the disorders of pigmentaion in Chinese population. It provides an alternative therapeutic choice for plastic surgeon or dermatologist to treat the skin disorders of pigmentation disease.
出处
《中华医学美学美容杂志》
2016年第2期87-89,共3页
Chinese Journal of Medical Aesthetics and Cosmetology
基金
国家高技术研究发展计划（863计划）（2014AA020705）
关键词
表皮细胞移植
自体
色素性病变
外科治疗
Epidermic cell transplantation, autologous
Disorders of pigmentation
Surgi- cal treatment
