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中国不同年龄段急性心肌梗死患者临床症状和诱发因素的差异分析 被引量:60

Age-related differences in the clinical symptoms and triggering factors among Chinese patients with acute myocardial infarction
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摘要 目的 探讨中国不同年龄段急性心肌梗死患者临床症状和诱发因素的差异.方法 入选中国急性心肌梗死注册登记(CAMI)研究2013年1月至2014年3月期间纳入的急性心肌梗死患者14 854例.将患者分为4组:<55岁组(3 950例);55- 64岁组(4 361例);65-74岁组(3 759例);≥75岁组(2 784例).收集患者的临床资料,比较各组患者之间临床症状和诱发因素的差异.结果 (1)急性心肌梗死患者的主要临床表现是持续性胸痛和大汗,分别占66.4%(9 863/14 854)和63.8%(9 471/14 854).<55岁组、55 -64岁组、65 -74岁组和≥75岁组患者发生持续性前胸剧痛的比例分别为73.8%(2 915/3 950)、69.2%(3 016/4 361)、63.6% (2 394/3 759)和55.2%(1 538/2 784),发生放射痛的比例分别为36.2%(1 428/3 950)、34.1%(1 487/4 361)、30.9%(1 160/3 759)和25.9%(722/2 784),出现大汗的比例分别为70.0% (2 765/3 950)、66.5% (2 898/4 361)、61.8%%(2 323/3 759)和53.3%(1 485/2 784),差异均有统计学意义(P均<0.001).(2)19.4%(2 879/14 854)的急性心肌梗死患者有明确的诱因.<55岁组、55-64岁组、65-74岁组和≥75岁组患者有诱因的比例分别为23.8% (941/3 950)、21.0%(914/4 361)、16.6% (625/3 759)和14.3%(399/2784),差异有统计学意义(P<0.001).<55岁组、55 -64岁组、65 -74岁组和≥75岁组患者近期过度不良生活方式的比例分别为20.8%(196/3 950)、11.9%(109/4361)、10.1%(63/3 759)和9.0%(36/2 784),差异有统计学意义(P<0.001).结论 中国近半数的≥75岁急性心肌梗死患者没有持续胸痛和大汗的典型临床症状.近1/5的患者心肌梗死前存在诱因,而且年轻患者更常见.临床研究注册号美国国立卫生研究院,注册号为NCT018746. Objective To analyze the age-related differences in the clinical symptoms and triggering factors among Chinese patients with acute myocardial infarction.Methods Acute myocardial infarction Patients (n =14 854) registered in the China Acute Myocardial Infarction Registry from January 2013 to March 2014 were included in this study.Patients were divided into 4 groups:〈55 years old group (3 950 patients),55-64 years old group (4 361 patients),65-74 years old group (3 759 patients),and ≥75 years old group (2 784 patients).Demographic features,medical history,clinical presentation and triggering factors were obtained via electronic data capture system.Results (1) Persistent chest pain and sweat were the major typical symptoms 66.4% (9 863/14 854) and 63.8% (9 471/14 854)) in the whole cohort.Prevalence of persistent chest pain among four groups were 73.8% (2 915/3 950),69.2% (3 016/ 4 361),63.6% (2 394/3 759) and 55.2% (1 538/2 784),and radiating pain among four groups were 36.2% (1 428/3 950),34.1% (1 487/4 361),30.9% (1 160/3 759) and 25.9% (722/2 784),and sweat among four groups were 70.0% (2 765/3 950),66.5% (2 898/4 361),61.8% % (2 323/3 759) and 53.3% (1 485/2 784),and there were statistical significance for all above symptoms among groups (all P 〈 0.001).(2)triggering factors before acute myocardial infarction could be found in 19.4% (2 879/14 854) of the patients.Prevalence of existed triggering factors among four groups were 23.8% (941/3 950),21.0% (914/4 361),16.6% (625/3 759) and 14.3% (399/2 784,P 〈 0.001).Recent excessive unhealthy lifestyles among four groups were 20.8% (196/3 950),11.9% (109/4 361),10.1% (63/3 759) and 9.0% (36/2 784) among the 4 groups (P 〈 0.001).Conclusions Persistent chest pain and sweat are absent in nearly half of Chinese patients in ≥75 years old group.Triggering factors prior to acute myocardial infarction could be evidenced in about twen
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2016年第4期298-302,共5页 Chinese Journal of Cardiology
基金 “十二五”国家科技支撑计划(2011BAI11B02) 公益性行业科研专项(201402001)
关键词 心肌梗死 症状和体征 年龄因素 Myocardial infarction Symptoms &amp signs Age factors
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参考文献11

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