摘要
目的 探讨新生儿缺氧缺血性脑病血小板参数的变化及对临床指导意义。方法 对 1999年 10月～ 2 0 0 1年 5月被确诊为HIE的 5 0例新生儿的血小板数 (PLT)、平均血小板体积 (MPV)及血小板体积分布宽度(PDW)进行动态观察 ,并与 2 7例正常足月儿对比。结果 ⑴HIE患儿急性期PLT较正常儿明显降低 (P <0 0 1) ,MPV和PDW较正常儿明显增高 (P <0 0 5 ) ,两组恢复期PLT、MPV、PDW之间无明显差异 (P >0 0 5 )。⑵HIE患儿PLT随HIE病情加重而降低 (P <0 0 1) ,而MPV、PDW则随病情加重而增大 (P <0 0 5 )。结论 动态观察HIE患儿血小板参数 ,可作为判断病情严重程度的指标。
Objective To explore the clinical effectiveness of the platelet parameter in neonatal hypoxic-ischemic encephalopathy(HIE).Methods From Oct,1999 to May 2001,50 cases of neonatal HIE were final diagnosed,the platelet total(PLT),mean platelet volume(MPV) and platelet distribution width(PDW) were dynamic observed.It was compared with 27 cases of normal term infant.Results ⑴PLT in acute period of HIE was obviously lower than that of the normal term infant(P<0 01).MPV and PDW were obviously high than that of the normal term infant(P<0 05).The PLT,MPV,PDW in the recovery period were no significantly different between the two groups(P>0 05).⑵The PLT in the HIE was decreased(P<0 01) and the MPV,PDW were increased(P<0 05) by the degree of severity.Conclusion It's a marker of evaluating the severity of HIE by dinanic observing the PLT parameter.
出处
《中国医师杂志》
CAS
2002年第8期811-812,共2页
Journal of Chinese Physician
