摘要
目的探讨无创心功能检测在高血压患者中的临床应用价值。方法选取我院收治的高血压患者150例作为研究对象,对所有患者均进行无创心功能检测,并按照心功能分级标准将其分为两组:心功能正常组65例,心功能异常组85例。记录两组患者的射血分数和左室舒张期终末压,并检测其脑钠尿肽水平,比较各项指标的检测结果及差异,并分析不同指标之间的相关性。结果心功能异常组患者的左室舒张期终末压及脑钠尿肽水平都显著高于心功能正常组,差异有统计学意义(P<0.05)。对心功能异常组不同心功能分级的各项指标检测结果进行比较,发现随着心功能分级的升高,射血分数越低,而左室舒张期终末压及脑钠尿肽水平逐渐升高,差异有统计学意义(P<0.05),且左室舒张期终末压和脑钠尿肽水平之间呈显著正相关。结论无创心功能检测能有效反映高血压患者的心脏损害程度,且检测安全、有效、可重复性好,具有较高的临床应用价值。
Objective To explore the clinical significance of non-invasive cardiac function detection for hypertension patients. Methods We selected 150 hypertension patients admitted in our hospital as research objects. All the cases were carried out non-invasive cardiac function detection and divided into two groups according to cardiac function classification criteria with 65 cases in normal group and 85 in abnormal group. The ejection fraction and left ventricular end-diastolic pressure were recorded among the two groups. Meanwhile,the brain natriuretic peptide level was detected.We compared the result of each index,and analyzed the relativity between different indices. Results The left ventricular end-diastolic pressure and brain natriuretic peptide level in abnormal group were significantly higher than those in normal group,with statistically significant differences（ P〈0. 05）. Among the abnormal group,we also compared the detection results of each index at different grade of cardiac function. It revealed that with the rise of the grade,the detection results of ejection fraction decreased while left ventricular end-diastolic pressure and brain natriuretic peptide level increased gradually,with statistically significant difference among the subgroups（ P〈0. 05）. In addition,the detection result of left ventricular end-diastolic pressure and brain natriuretic peptide level were significantly positively correlated. Conclusion Non-invasive cardiac function detection caneffectively reflect the severity of heart lesion for hypertension patients. It proves to be safe,effective,reproducible and has high value in clinical application.
出处
《实用心电学杂志》
2016年第2期106-108,共3页
Journal of Practical Electrocardiology
基金
重庆市科委自然科学基金资助项目(CSTC2009BB5332)
关键词
无创心功能检测
高血压
射血分数
舒张期终末压
non-invasive cardiac function detection
hypertension
ejection fraction
enddiastolic pressure
