摘要
目的:探讨重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)治疗酒依赖者失眠的临床疗效。方法:将70例酒依赖伴随失眠患者,随机分为rTMS组和对照组各35例,rTMS组采用rTMS治疗,对照组采用伪rTMS治疗,2组患者均给予刺激1次·d^(-1),20min·次^(-1),连续治疗4周。采用匹兹堡睡眠质量指数问卷、多导睡眠监测睡眠潜伏期、觉醒次数及睡眠觉醒时间评定疗效,比较两组治疗前、后临床疗效。结果:rTMS组患者治疗后匹兹堡睡眠质量指数明显低于治疗前及对照组(P<0.01);多导睡眠监测睡眠潜伏期、觉醒次数及觉醒时间较治疗前及对照组均明显减少(P<0.01)。结论:rTMS可显著缩短酒依赖伴随失眠患者的睡眠潜伏期、减少觉醒次数及觉醒时间,治疗酒依赖者失眠疗效可靠。
Objective：To investigate the effect of repetitive transcranial magnetic stimulation（ r MS） on insomnia with alcohol- dependence.Methods：Seventy patients of insomnia with alcohol dependence were randomly divided into the r MS group and the control group,with thirty- five patients in each group. Patients in the r MS group were treated with r MS,while patients in the control group received sham r MS,for twenty minutes each time,once a day,and totally for four weeks. The Pittsburgh sleep quality index questionnaire,sleep latency,number of awakening and awakening time on polysomnography were evaluated and the clinical efficacy was compared before and after four weeks treatment between the two groups.Results：Pittsburgh sleep quality index was significantly lower,and the sleep latency,number of awakening and awakening time on polysomnography were significantly shorter after MS treatment than those before treatment and those in the control group（ P 〈0. 01）.Conclusion：r MS can significantly shorten the sleep latency time,number of awakening and awakening time in the patients of insomnia with alcohol dependence. It is reliable and effective for r MS to treat insomnia with alcohol dependence.
出处
《中国药物依赖性杂志》
CAS
CSCD
2016年第2期206-208,共3页
Chinese Journal of Drug Dependence
关键词
重复经颅磁刺激
酒依赖
失眠
repetitive transcranial magnetic stimulation
alcohol dependence
insomnia
