摘要
目的探讨温肾化痰方加减治疗老年慢性肾功能不全的临床疗效。方法选取2013年4月至2014年4月攀枝花市中西医结合医院收治的80例老年慢性肾功能不全患者为研究对象,采用随机数字表法分为对照组和试验组,各40例。对照组采用传统西药治疗,试验组采用温肾化痰法加减治疗,比较两组患者的临床疗效。结果试验组总有效率显著高于对照组[95.0%(38/40)比80.0%(32/40),P<0.05];治疗后,试验组中医症状积分、血肌酐、尿氮素以24 h尿蛋白定量显著低于对照组[(5.9±1.4)分比(8.8±1.6)分,(64.3±2.3)mmol/L比(89.4±2.6)mmol/L,(4.7±0.8)mmol/L比(6.6±1.3)mmol/L,(79±10)mg比(137±14)mg,P<0.01];治疗后,试验组总胆固醇、三酰甘油、低密度脂蛋白胆固醇显著低于对照组[(3.53±0.67)mmol/L比(5.02±1.12)mmol/L,(1.44±0.39)mmol/L比(1.81±0.48)mmol/L,(2.14±0.25)mmol/L比(3.32±0.67)mmol/L,P<0.01],试验组高密度脂蛋白胆固醇显著高于对照组[(1.53±0.42)mmol/L比(1.25±0.36)mmol/L,P<0.01]。结论老年慢性肾功能不全患者采用温肾化痰方加减治疗效果理想,值得推广使用。
Objective To investigate the clinical efficacy of warming kidney phlegm elimination therapy addition and subtraction in elderly patients with chronic renal insufficiency. Methods Total of 80 elderly patients with chronic renal insufficiency admitted to Panzhihua City Integrative Medicine Hospital from Apr.2013 to Apr. 2014 were included in the study and divided into control group andtrial group. The control group adopted traditional western medicine,and the trial group adopted warming kidney phlegm elimination therapy addition and subtraction,and the clinical efficacy of the two groups was compared. Results The total effective rate of the trial group was significantly higher than the control group[95. 0%（ 38 /40） vs 80. 0%（ 32 /40）,P〈 0. 05]; the Chinese medicine symptom score,serum creatinine,urine nitrogen and 24 h urine protein quantitative indicators of the trial group were significantly lower than the control group [（ 5. 9 ± 1. 4）scores vs（ 8. 8 ± 1. 6） scores,（ 64. 3 ± 2. 3） mmol / L vs（ 89. 4 ± ± 2. 6） mmol / L,（ 4. 7 ± 0. 8） mmol / L vs（ 6. 6 ± 1. 3） mmol / L,（ 79 ± 10） mg vs（ 137 ± 14） mg,P〈 0. 01]; after treatment total cholesterol,triacylglycerol,low density lipoprotein cholesterol of the trial group were significantly lower than the control group[（ 3. 53 ±0. 67） mmol/L vs（ 5. 02 ±1. 12） mmol/L,（ 1. 44 ± 0. 39） mmol/L vs（ 1. 81 ± 0. 48） mmol/L,（ 2. 14 ±0. 25） mmol/L vs（ 3. 32 ±0. 67） mmol/L,P〈 0. 05]; the HDL-C of the trial group was significantly higher than the control group[（ 1. 53 ± 0. 42） mmol / L vs（ 1. 25 ± 0. 36） mmol / L,P〈 0. 05]. Conclusion Warming kidney phlegm elimination therapy addition and subtraction for elderly patients with chronic renal insufficiency has satisfactory effect,thous should be promoted.
出处
《医学综述》
2016年第8期1652-1655,共4页
Medical Recapitulate
关键词
慢性肾功能不全
老年
温肾化痰法
Chronic renal insufficiency
Elderly
Warming kidney phlegm elimination therapy
