摘要
目的:观察前列康巴布贴贴脐治疗慢性非细菌性前列腺炎(CAP)的疗效,探索其对CAP患者前列腺液(EPS)中IFN-γ表达的影响。方法:招募30名正常成年男性作为正常组,将60例CAP患者随机分为治疗组和对照组各30例。正常组不予以任何药物处理,治疗组予以前列康巴布贴贴脐,对照组予以前列安栓塞肛。治疗90 d,评价两组的疗效,观察比较两组中医证候积分、前列腺炎症状积分指数(NIH-CPSI)评分并检测两组治疗前后及正常组EPS-IFN-γ浓度。结果:治疗组中医证候疗效优于对照组(P<0.01),治疗后中医证候积分、NIH-CPSI积分及IFN-γ浓度均低于对照组(P<0.05或P<0.01)。结论:前列康巴布贴贴脐治疗CAP疗效显著;CAP患者EPS-IFN-γ浓度明显高于正常人群;前列康巴布贴可降低CAP患者EPS-IFN-γ浓度。
Objective： To observe the curative effect of Qianliekang cataplasms on chronic abacterial pro- statitis （CAP） and to explore its influence on the expression of IFN-y Methods： Recruiting 30 normal adult male as normal group, 60 patients with CAP were randomly divided into treatment group and control group, 30 cases each. The normal group did not accepted any drug treatment, the treatment group was stucked with Qian- liekang cataplasms on the navel, and the anal control group was plugged with Qianliean suppository into the anal. Treatment for 90 days, then the curative effects of two groups, the integral of TCM symptom and prostate gland inflammation shape integral index （NIH-CPSI） and the density of IFN-y in the prostatic fluid of the treatment group, control group and the normal group before and after the treatment were evaluated, and record- ed. Results： The total effective rate and comprehensive effect of the treatment group was better than the control group （P〈0.01）, and the TCM symptoms integral, the NIH-CPSI integral and IFN-y density after treatment were all lower than the control group （P〈0.05 or P〈0.01）. Conclusions： The therapeutic effect of Qianliekang cata- plasms stcuk on the navel of patients with CAP is significant. The IFN-y concentration of prostate fluid of pa- tients who suffer from CAP is significantly higher than the general population, and Qianliekang cataplasms can make CAP patients＂ density of IFN-y in prostate fluid decreased obviously.
出处
《中医药导报》
2016年第8期67-69,共3页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
湖南省自然科学基金项目(湘财企指[2013]139号)
湖南省教育厅中医外科重点学科经费资助
