摘要
目的:探讨碳酸锂对双相障碍男性患者甲状腺功能的影响。方法:选取符合诊断标准的152例双相障碍男性患者给予碳酸锂治疗1个月,分别在治疗前和治疗1个月后检测血浆游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、三碘甲状腺原氨酸(T3)、甲状腺素(T4)和促甲状腺激素(TSH)水平。结果:治疗后,患者血浆FT3(2.65±0.32)pg/ml、FT4(0.80±0.12)ng/dl水平低于治疗前,差异有统计学意义(P<0.01)。结论:锂盐对双相障碍男性患者甲状腺功能改变存在影响。
Objective To determine effects of lithium carbonate on thyroid function in male patients with bipolar disorders.Methods： 152 male patients with bipolar disorders were treated with lithium carbonate for 1 month. The levels of plasma free triiodothyronine （FT3）, free thyroxine （FT4）, triiodothyronine （T3）, thyroxin （T4） and thyroid-stimulating hormone （TSH） before and 1month after the treatment were detected. Results： The FT3 （2. 65依0. 32 pg/ ml） and FT4 （0. 80依0. 12 ng/ dl） levels after the treatment were lower than those before the treatment, and the differences were statistically significant （P〈0. 01）. Conclusions： Lithiumsalt may be associated with changes of the thyroid function in the male patients with bipolar disorders.
出处
《中国民康医学》
2016年第6期8-10,共3页
Medical Journal of Chinese People’s Health
关键词
双相障碍
锂盐
甲状腺功能
Bipolar disorder
Lithium salt
Thyroid function
