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中央型肺癌行肺动脉成形肺叶切除与全肺切除对比研究 被引量:2

A comparative study between pulmonary lobectomy and pneumonectomy in central type lung cancer
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摘要 目的 对比中央型肺癌行肺动脉成形肺叶切除与全肺切除术后并发症及疗效。方法 回顾分析2001年1月~2009年1月,64例中央型肺癌分为肺动脉成形肺叶切除组(后简称肺叶切除组)与全肺切除组进行对比,分析术后并发症、术后1、3、5年生存率及Karnofsky评分。结果 64例患者手术均顺利完成,肺叶切除组与全肺切除组在术中出血量、淋巴结清扫数、住院时间及术后1、3、5年生存率方面比较,均无统计学差异(P〉0.05)。肺叶切除组术后并发症发生率少于全肺切除组,而手术时间及1、3、5年Karnofsky评分大于全肺切除组,差异均有统计学意义(P〈0.05)。结论 中央型肺癌行肺动脉成形肺叶切除对比全肺切除,虽手术时间稍长,但术后并发症减少,术后生活质量提高,术后1、3、5年生存率无统计学差异,临床适合采用。 Objective To compare the postoperative complications and curative effect of pulmonary lobecto- my with pneumonectomy in central type lung cancer. Methods The clinical data of 64 cases of central type lung cancer from January 2001 to January 2009 were retrospectively analyzed. All the patients were performed surgical treatment with either pulmonary lobectomy or pneumonectomy, and they were accordingly divided into the pulmonary lobectomy group and the pneumonectomy group to compare postoperative complications, 1, 3, 5 years postoperative survival rate and Karnofsky score. Results The operations of 64 cases were all successfully performed. There was no significant statistical difference in lymph node operating time, intraoperative blood loss, duration of hospital stay and 1, 3, 5 years postoperative survival rate between the two groups (P 〉 0. 05 ). However, the occurrence of postopera- tive complications in the lobectomy group was obviously lower than that in the pneumonectomy group ( P 〈 0.05 ), and the lobectomy group also achieved significant higher 1, 3, 5 years Karnofsky score than that of the pneumonecto- my group ( P 〈 0. 05 ). Conclusion Compared with pneumonectomy performed on patients with central type lung cancer, pulmonary lobeetomy with pulmonary artery forming shows more promises on improvement of postoperative quality of life, lower occurrence of postoperative complications. Pulmonary lobectomy may take longer operation time, but there is no significant statistical difference in overall 1, 3, 5 years postoperative survival rate.
出处 《临床肺科杂志》 2016年第5期889-892,共4页 Journal of Clinical Pulmonary Medicine
关键词 中央型肺癌 肺动脉成形 肺叶切除 全肺切除 central type lung cancer pulmonary artery forming lobectomy pneumonectomy
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