摘要
目的探讨戊酸雌二醇联合米非司酮、米索前列醇治疗稽留流产对患者术后生活质量的影响。方法选取2015年医院收治的稽留流产患者80例,按随机数字表法将其分为对照组(米非司酮联合米索前列醇治疗)和观察组(戊酸雌二醇联合米非司酮及米索前列醇治疗),各40例。比较两组患者术中情况、急诊清宫及人工流产综合征发生率及术后生活质量。结果与对照组相比,观察组妊娠组织物排出率、宫颈扩张满意度均明显增高(90.00%比67.50%,87.50%比62.50%,P<0.05),术中出血量明显减少(P<0.05);观察组急诊清宫率、人工流产综合征发生率均显著降低(0比10.00%,2.50%比15.00%,P<0.05);观察组生活质量各维度得分及总分均明显增高(P<0.05)。结论戊酸雌二醇联合米非司酮及米索前列醇治疗稽留流产可明显提升患者术后生活质量,值得推广。
Objective To study the influence of estradiol valerate combined with mifepristone,misoprostol in the treatment of missed abortion on the quality of postoperative life of patients.Methods Totally 60 patients with missed abortion in the hospital in 2015 were divided into the control group（treatment of mifepristone and misoprostol） and the observation group（treatment of estradiol valerate com-bined with mifepristone,misoprostol） according to the random number method,30 patients in each group.The pregnancy tissue removal rate,cervical dilatation satisfaction degree,bleeding volume,postoperative bleeding time,and the incidence of emergency curettage and ar-tificial abortion syndrome in two groups were compared.Results Compared with the control group,the pregnancy tissue removal rate and cervical dilatation satisfaction degree were significantly increased in the observation group（90.00% vs67.50%,87.50% vs 62.50%,P〈0.05）;the bleeding volume and postoperative bleeding time were obviously reduced in the observation group（P〈0.05）;the incidence of emergency curettage and artificial abortion syndrome were significantly decreased in the observation group（0 vs 10.00%,2.50% vs 15.00%,P〈0.05）.The scores of each dimension and total score of life quality were significantly increased in the observation group（P〈0.05）. Conclusion The treatment of estradiol valerate combined with mifepristone,misoprostol is the safe and effective method and is worthy of clinical promotion.
出处
《中国药业》
CAS
2016年第6期40-41,共2页
China Pharmaceuticals
