摘要
目的:基于专利文献深入分析天然抗肿瘤药制剂技术的发展态势。方法:采用专利计量分析、统计学趋势分析等定量分析方法结合药学专业知识的定性分析方法从专利申请数量、国家/地区分布、专利技术领域等方面对天然抗肿瘤药制剂技术领域的发展态势进行分析。结果:天然抗肿瘤药制剂技术专利年申请数量在3000件左右,处于比较稳定平稳的发展时期;专利申请主要集中在美国和中国;专利技术领域主要集中在抗肿瘤活性和剂型的相关研究。结论:美国专利申请数量排名第一,远远领先于其他国家,且专利质量很高,处于绝对的领先地位。中国虽然在专利申请数量方面具有一定优势,但是专利质量亟待提高,与国外发达国家相比仍有较大差距。
To deeply analyze development trends of preparation technology in natural antineoplastic agents based on patents. Methods： The methodology included the quantitative analysis including patentometrics, single factor linear regression analysis and the qualitative analysis by professional knowledge in the fields of pharmaceuticals. This study mostly discussed patent applications,country/region distribution, technical fields and other aspects. Results： The numbers of patent applications were about 3000 one year,relatively stable in recent years; patent applications are mainly in the United States and China; technical fields are mainly concentrated in antineoplastic activity and preparation. Conclusions： The numbers of patent applications in the United States is far ahead of other countries, owing strong technological strength. Although China has certain advantages in the number of patent applications, there is still a wide gap compared with foreign countries.
出处
《现代生物医学进展》
CAS
2016年第8期1546-1550,共5页
Progress in Modern Biomedicine
基金
北京协和医学院协和青年基金和中央高校基本科研业务费专项(3332013151)
中国医学科学院医学信息研究所中央级公益性科研院所基本科研费项目(12R0113)
中国医学科学院/北京协和医学院药物研究所天然药物活性物质与功能国家重点实验室开放课题(GTZK201508)
关键词
天然产物
抗肿瘤药
制剂技术
专利分析
发展态势
Natural products
Antineoplastic agents
Preparation technology
Patent analysis
Development trends
