摘要
目的比较不同用药方案在无痛人工流产术前应用的宫颈扩张效果。方法选择安阳市第三人民医院2013年3月至2014年9月收治的120例孕妇作为研究对象，分为两组。A组人工流产术前口服50mg米非司酮、阴道给药200μg米索前列醇；B组术制阴道给药400μg米索前列醇，比较两组术中宫颈扩张度、手术时间、术中出血量等手术指标及药物不良反应发生率。结果两组宫颈扩张度、手术时间、术中出血量等的比较差异均未见统计学意义（P〉0．05）。A组恶心呕吐、腹痛、阴道流血、头晕寒战等不良反应发生率均显著低于B组，差异有统计学意义（P〈0．05）。结论米索前列醇联合米非司酮在无痛人工流产术前的应用具有较好的宫颈扩张效果，药物不良反应减少，安全性更高，值得临床借鉴。
Objective To compare the effect of different prescriptions on cervical dilation before painless artificial abortion. Methods One hundred and twenty pregnant women admitted into the third people＇ s hospital of Anyang from March 2013 to September 2014 were selected as the research objects and divided into two groups. Group A： 50 mg mifepristone orally and 200 μg misoprostol in vaginae before artificial abortion, group B： 400 μg misoprostol in vaginae. The degree of cervical dilation, operative time, the volume of intraoperative bleeding and other operative indexes and the incidence of drug adverse reactions of the two groups were compared. Results There were no significant differences in the degree of cervical dilation, operative time, the volume of intraoperative bleeding or other operative indexes between the two groups （P 〉 0.05 ）. The occurrence rates of adverse reactions such as nausea and vomiting, abdominal pain, vaginal bleeding, dizziness and chills of group A were significantly lower than those of group B, the differences were significant （ P 〈 0. 05 ）. Conclusions Mifepristone combined with misoprostol has good effect on cervical dilation before painless artificial abortion, and the adverse reactions of drugs can be reduced. It has higher security, worthy of clinical reference.
出处
《中国实用医刊》
2016年第5期34-35,共2页
Chinese Journal of Practical Medicine
关键词
人工流产
用药方案
宫颈扩张
不良反应
Artificial abortion
Prescriptions
Cervical＇dilatation
Adverse reaction
