摘要
目的了解综合医院抗真菌药物使用情况及深部真菌感染情况,分析深部真菌感染的临床流行病学。方法回顾性分析综合医院2015年1~6月接收的3 728例患者的病历资料,统计抗真菌药物及深部真菌感染情况,分析深部真菌感染临床流行病学特征。结果 3 728例患者中,44例患者使用抗真菌药物,占1.1%,发生深部真菌感染28例,占63.6%。深部真菌感染主要发生于60岁以上老年患者,多发于肺部及口腔,致病菌种主要为白假丝酵母菌,高危因素为长期使用抗生素、糖皮质激素、免疫抑制剂及化疗药物。结论深部真菌感染主要发生于肺部及口腔部位,临床中应十分重视真菌感染预防,合理使用抗真菌药物,降低深部真菌感染发生率。
Objective To understand the general hospital antifungal drug usage, and deep fungal infection, clinical epidemiological analysis of deep fungus infection. Methods To retrospectively analyze general hospital from January to June 2015 medical records of 3 728 patients receiving, statistics of antifungal drugs and deep fungal infection, analysis of clinical epidemiological characteristics of deep fungus infection. Results 3 728 cases of patients, the use of antifungal drugs, 44 patients for 1.1%, 28 cases of deep fungal infection, accounting for 63.6%. Deep fungal infection is mainly occurred in elderly patients over 60, happens in the lungs and mouth, pathogenic bacteria species mainly white candida, risk factors for long-term use of antibiotics, glucocorticoid and immunosuppressants and chemotherapy drugs. Conclusion Deep fungal infection occurred mainly in the lungs and mouth part, should attach great importance to fungal infection in clinical prevention and rational use of antifungal drugs, reduce the incidence of deep fungal infection.
出处
《中国继续医学教育》
2016年第7期24-25,共2页
China Continuing Medical Education
关键词
抗真菌药物
深部真菌感染
流行病学
Antifungal drugs
Incidence of deep fungal infection
Epidemiology
