摘要
目的 对患有药物性皮损伴系统性损害患者的致敏药物类别及排序、临床表现、治疗及转归进行临床分析.方法 随机选取198例药物性皮损伴系统性损害患者,采用回顾性方法对这些患者的临床资料进行分析.结果 ①抗生素类药物成为引起药物性皮损伴系统性损害的首要因素,占52.6%;其次为解热镇痛类药物,占24.8%;血清制品及生物制品占 7.9%;中药占5.7%;镇静安眠类占3.4%;其他药物占5.6%.②药物性皮损的皮疹类型主要为荨麻疹,其次为猩红热样或麻疹样红斑.③药物性皮损伴系统性损害患者的年龄分布以中青年患者居多,且老年药物性皮损呈上升趋势.④受累器官：依次为肾脏、心脏以及肝脏.结论 药物性皮损伴系统性损害的致敏药物以抗生素为主,受累脏器以肾脏为主,药物性皮损的皮疹类型主要为荨麻疹.
Objective Analysis of the types , clinical manifestations, treatment and prognosis of drug-induced skin lesions.Methods Randomlyselected 198 cases of drug-induced skin lesions with systemic damage,and the clinical data of these patients were analyzed by retrospectivemethod.Results Antibiotics are the most important factors that cause systemic lesions in the skin lesions,It accounts for 52.6%;Second factors forantipyretic analgesic drugs,It accounts for 24.8%;The type of rash is mainly urticaria,and scarlatiniform or morbilliform erythema.Age distributionof patients with drug-induced skin lesions and systemic lesionsYoung and middle-aged patients are in the majority, and the aging of the skin lesionsshowed an upward trend.④Involved organs：Kidneys, heart, and liver.Conclusions Antibiotics are the main cause of drug resistance and systemicdamage in the skin lesions.Kidney is the main organ involved.The main types of drug eruption were urticaria.
出处
《中华临床医师杂志（电子版）》
CAS
2016年第4期114-114,共1页
Chinese Journal of Clinicians(Electronic Edition)
关键词
药物性皮损
系统性损害
临床分析
Drug induced lesion
systemic lesion
clinical analysis
