摘要
目的探讨在外周神经电刺激引导下A型肉毒毒素（BTX-A）局部注射治疗面肌痉挛的疗效。方法 2012年1月~2015年6月,57例面肌痉挛患者在外周神经电刺激引导下采用BTX-A局部多点注射。治疗前、治疗后72 h和6个月,进行面肌痉挛强度评级,根据面肌痉挛强度评级进行疗效评定。随访3~9个月。结果患者治疗后面肌痉挛强度均较治疗前改善。治疗72 h后有效率为98.25%,治疗6个月后有效率为91.23%（χ^2=4.946,P〈0.05）;疗效平均维持（23.1±2.3）周。结论外周神经电刺激引导下BTX-A局部多点注射治疗面肌痉挛疗效显著且持久。
Objective To investigate the effects of local injection of Botulinum toxin A（BTX-A） on hemifacial spasm guided by peripheral nerve stimulation. Methods 57 patients with hemifacial spasm from January, 2012 to June, 2015 received local multi-point injection of BTX-A guided by peripheral nerve stimulation. The grades of facial spasm were evaluated before, 72 hours and 6 months after treatment.They were followed up for 3-9 months. Results The spasm reduced in the patients both 72 hours and 6 months after treatment（χ^2=4.946, P〈0.05）. The incidence was 98.25% of satisfaction and 92.99% of very well 72 hours after treatment, while it was 91.23% and 78.95% 6months after treatment. The relief of spasm was maintained for（23.1 ± 2.3） weeks. Conclusion Injection of BTX- A guided by peripheral nerve stimulation is effective on hemifacial spasm for a long time.
出处
《中国康复理论与实践》
CSCD
北大核心
2016年第3期323-325,共3页
Chinese Journal of Rehabilitation Theory and Practice
关键词
面肌痉挛
A型肉毒毒素
外周神经电刺激
hemifacial spasm
Botulinum toxin A
peripheral nerve stimulation
