摘要
目的探讨右美托咪定联合舒芬太尼在老年患者骨关节术后镇痛的效果。方法选择我院120例患者为研究对象,随机分为对照组与观察组,均行气管插管下全身麻醉,术后行自控静脉镇痛,观察组镇痛药物为右美托咪定联合舒芬太尼,对照组为舒芬太尼。结果观察组术后4、12与48 h疼痛评分均明显小于对照组,镇静评分明显高于对照组(均P<0.05)。两组均未发生呼吸抑制,与对照组相比,观察组恶心、呕吐的发生率明显较低(P<0.05)。结论舒芬太尼复合右美托咪定用于老年患者骨关节术后镇痛与镇静的效果更好,且安全性好,值得推广应用。
Objective To explore the analgesic effect of dexmedetomidine combined with sufentanil on elderly patients after bone joint surgery. Methods 120 elderly patients were chosen as research objects and randomly divided into control and observation groups. All the patients received general anesthesia under tracheal intubation and postoperative self-controlled intravenous analgesia.The analgesic drugs for the observation group were dexmedetomidine combined with sufentanil, and the drug for the control group was sufentanil. Results The pain scores of the observation group 4, 12, and 48 h after the operation were significantly smaller than those of the control group（P〈0.05）. Respiratory depression did not occur in the two groups. Compared with the incidence of nausea and vomiting in the control group, that in the observation group was significantly lower（ P〈0.05）. Conclusion Dexmedetomidine combined with sufentanil has superior analgesic and sedative effects on elderly patients after bone joint surgery, which has good safety and is worthy of promotion and application.
出处
《西南国防医药》
CAS
2016年第4期359-361,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
右美托咪定
舒芬太尼
骨关节
术后
镇痛
老年
dexmedetomidine
sufentanil
bone joint
postoperative
analgesia
elderly
