摘要
目的探讨电针对超排卵小鼠胚胎发育状况的影响。方法将雌性小鼠随机分成自然组、阴性对照组、超排卵组和电针组,取三阴交、关元、中极行电针治疗,每天1次。根据胚胎发育情况及囊胚评价系统观察胚胎的质量变化。结果超排卵组获得的胚胎数最多,优质胚胎率较低,且3~6级囊胚率最低;电针组与超排卵组相比,获得囊胚率虽无统计学意义(P〉0.05),但优质囊胚率及3~6级囊胚率均高于超排卵组,且差异有统计学意义(P〈0.05)。结论针刺可以改善超排卵小鼠的胚胎质量,从而提高着床率。
Objective To explore effects of electroacupuncture on embryo quality in superovulating mice. Methods 60 female mice were randomly divided into natural group,negative control group,superovulating group and electroacupuncture group. Acupuncture group was treated with electroacupuncture on Sanyinjiao( SP6),Guanyuan( RN3) and Zhongji( RN4). Embryonic quality was evaluated based on the embryonic development status and blastula evaluation system. Results Superovulating group presented with the most number of embryos. High-quality embryo rate was relatively low. Moreover,the rate of Grade 3 ~ 6 blastocyst was the lowest in superovulating group. Compared with superovulating group,blastocyst rate in the electroacupuncture group was not significantly different( P〉 0. 05). However,rates of high-quality blastocyst and Grade 3 ~ 6 blastocyst were higher than the superovulating group with statistical significance( P 〈0. 05). Conclusion Acupuncture can improve embryo quality in superovulating mice and possibly improve implantation rate.
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
2016年第2期169-172,共4页
Journal of Beijing University of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(No.81373725)
关键词
针刺
胚胎质量
着床率
小鼠
acupuncture
embryo quality
implantation rate
mouse