摘要
目的：探讨腹腔镜下腹腔置管灌洗引流治疗重症急性胰腺炎（SAP）的临床疗效。方法：收集2009年1月至2014年5月的87例SAP患者资料,包括腹腔镜腹腔灌洗（LPLD）组46例和内科综合治疗组（非LPLD组）41例。LPLD组于发病1~2周内进行LPLD,余同非LPLD组治疗。分析比较两组患者的住院时间和ICU治疗时间,以及治愈率、并发症发生率和住院死亡率。结果：LPLD组住院时间、ICU治疗时间均少于非LPLD组,LPLD组的治愈率优于非LPLD组,差异均有统计学意义（P〈0.05）;两组并发症发生率比较,脓毒血症发生率差异有统计学意义（P〈0.05）,余差异均无统计学意义（P〉0.05）;两组住院病死率比较,差异无统计学意义（P〉0.05）。结论：腹腔镜灌洗治疗SAP短期获益更显著,是治疗SAP行之有效的手段,值得临床推广。
Objective To explore the effect of LPLD（laparoscopic peritoneal lavage and drainage） on SAP（severe acute pancreatitis）, and to compare its effect with that of non- LPLD（conservative medical management）. Methods We collected data from 87 consecutive patients with SAP, from January 2009 to May2014, including LPLD group（n = 46） and non-LPLD group（n = 41）. LPLD was performed in the 1st and 2nd week after the disease onset in LPDP group and other treatment in LPDP group was the same as that in nonLPLD group. Data were comparatively analyzed in two groups about the length of hospital stay, ICU stay, cure rate, incidence of complications and in-hospital mortality. Results In LPLD group, hospital stay, and ICU stay were shorter while cure rate was higher than those in non-LPLD group, and the difference was statistically significant（P〈0.05）. In terms of the incidence of complications in two groups, only the incidence of sepsis indicated statistical significance（P〈0.05） and in-hospital mortality did not differ significantly between two groups（P〉0.05）. Conclusion Compared with non-LPLD, LPLD is effective in short outcome, which is a promising treatment for SAP.
出处
《实用医学杂志》
CAS
北大核心
2016年第6期903-907,共5页
The Journal of Practical Medicine
基金
广东省自然科学基金(编号:2014A030310393)
南宁市普通外科腔镜微创中心建设(编号:20153012)
关键词
重症急性胰腺炎
腹腔镜置管灌洗引流
多器官功能衰竭
Laparoscopic peritoneal lavage and drainage
Severe acute pancreatitis
Multiple organ failure
