摘要
目的 探讨该地新生儿早产的可能危险因素,为新生儿早产的病因学研究提供科学依据。方法 采用1∶2配对病例对照研究方法,选取2014年5月-11月期间在西安交通大学第一附属医院住院分娩的早产产妇130例和260名正常分娩产妇进行回顾性分析;采用单因素和多因素条件Logistic逐步回归进行新生儿早产危险因素分析。结果 单因素χ2检验结果显示,从事体力劳动者、人工流产史、妊娠期高血压疾病、胎膜早破、前置胎盘、臀位与早产的发生有统计学关联(P〈0.05)。多因素条件Logistic回归分析显示,从事体力劳动者(OR=2.572,95%CI:1.071-6.174)、妊娠期高血压疾病(OR=29.704,95%CI:10.805-81.655)、胎膜早破(OR=5.774,95%CI:2.814-11.845)、前置胎盘(OR=42.228,95%CI:9.509-187.522)、臀位(OR=5.462,95%CI:1.772-16.839)是新生儿早产的危险因素。结论 早产的危险因素是多方面的,需采取综合的防治措施。
Objective To explore the risk factors of premature delivery, provide a scientific basis for studying the causes of premature delivery. Methods A 1. 2 matched case-control study was preformed, 130 premature delivery cases and 260 control cases from the First Affiliated Hospital of Xi'an Jiaotong University from May to November in 2014 were analyzed retrospectively. The risk factors of premature delivery were analyzed by univariate and multivariate conditional logistic stepwise regression analysis. Results Univariatex2 test showed that manual work, history of induced abortion, hypertensive disorder complicating pregnancy (HDCP) , premature rupture of fetal membrane (PROM), placenta previa, and breech presentation were correlated with premature delivery (P〈0. 05 ) . Multivariate conditional logistic regression analysis showed that manual work ( OR= 2. 572, 95% CI: 1. 071-6. 174) , HDCP ( OR=29. 704, 95% CI: 10. 805-81. 655) , PROM ( OR = 5. 774, 95% CI: 2. 814-11. 845 ), placenta previa ( OR = 42. 228, 95% CI: 9. 509-187. 522 ), and breech presentation ( OR= 5. 462, 95% CI: 1. 772-16. 839) were risk factors of premature delivery. Conclusion Comprehensive measures should be taken to prevent and treat premature delivery caused by many factors.
出处
《中国妇幼保健》
CAS
2016年第7期1395-1397,共3页
Maternal and Child Health Care of China
基金
国家自然科学基金资助(81230016)
关键词
早产
危险因素
配对病例对照研究
Premature delivery
Risk factor
Matched case-control study