摘要
目的评估圆锥角膜患者长期配戴硬性透气性角膜接触镜(RGP)后的视觉相关生活质量。方法收集2007年6月至2013年9月就诊于北京同仁医院眼科中心的37例初次配戴RGP治疗的圆锥角膜患者。采用美国国立眼科研究院视功能问卷(NEI-VFQ-25)中文版对纳入病人的视觉相关生活质量进行评定。对符合正态分布的数据采用两独立样本t检验,非正态分布的数据运用Wicoxon秩和检验。用Spearman等级相关分析双眼视力与各维得分的相关性。结果纳入分析的37例问卷中,男性23例,女性14例,平均年龄(20.5±4.0)岁;轻中度圆锥角膜21例,重度圆锥角膜16例。男女组量表得分差异无统计学意义,轻中度和重度组患者在近距离活动、依赖程度、社会角色限制三项维得分的差异有统计学意义。总体视力、近距离活动、远距离活动、周边视力、社会功能、社会角色限制、精神健康、依赖程度这八项的得分与较好眼视力均有较强相关性(rs>0.7,P<0.05),各项维得分与较差眼视力的相关性无统计学意义。结论配戴恰当的RGP镜片能显著提高圆锥角膜患者的视觉相关生活质量;视觉相关生活质量的问卷调查对临床上评估不同程度圆锥角膜患者配戴RGP镜片后的疗效有一定的补充作用。
OBJECTIVE To evaluate the vision-related quality of life in keratoconus patients with Rigid gaspermeable lens（RGP）. METHODS Recruited 37 keratoconus patients with RGP treated in Optometry center in Beijing Tongren Eye Center from July 2007 to July 2008. Vision-related quality of life was evaluated by the 25-item National Eye Institute Visual Functioning Questionnaire. Statistical analysis was performed using test for data which were normal distribution and using Wilcoxon rank sum test for data which were abnormal distribution. Spearman rank correlation analysis was performed to evaluate the relationship between NEI-VFQ-25 scores and VA（visual acuity）.RESULTS Regarding the subjective criteria, there was no significant difference on NEI-VFQ scores between two gender groups. It appeared siginificant difference on near activities,dependency as well as social role restriction between the two groups based on severity classification. Visual acuity of the better eye was strongly correlated with NEI-VFQ-25 scores. CONCLUSIONS Appropriate correction with RGP lenses could significantly improe VR-QOL for keratoconic patients; It was suggested that NEI-VFQ-25 questionare was meaningful for patients, their families, optometrists and ophthalmologists to correctly evaluate the keratoconus in clinical practice.
出处
《中国中医眼科杂志》
2016年第1期35-40,共6页
China Journal of Chinese Ophthalmology
基金
国家自然科学基金重点项目(11232013)
国家自然科学基金(10772124)
北京市卫生系统高层次卫生技术人才基金资助(20113046)
