摘要
目的探讨我国最新急性细菌性结膜炎致病菌的种类。方法对50例(50眼)急性细菌性结膜炎患者结膜囊分泌物进行细菌学检查,给予患者10 g·L^(-1)阿奇霉素滴眼液滴眼,每天2次,滴眼2 d后改为每天1次,治疗3 d,于第8天再次行细菌培养检查。结果急性细菌性结膜炎结膜囊分泌物细菌培养阳性率80.0%,革兰阳性细菌占97.5%,表皮葡萄球菌占首位(占培养阳性总数72.5%),其中包括2例苯唑西林耐药表皮葡萄球菌。应用抗生素治疗后,47例(94.0%)患者临床症状缓解。再次行病原学检查,原致病菌全部清除率为60.0%,部分清除率为5.0%。治疗后细菌培养仍阳性细菌主要为表皮葡萄球菌(占培养阳性总数56.2%)。结论表皮葡萄球菌已成为我国目前急性细菌性结膜炎的首要致病菌,在临床工作中应对其予以重视,选择针对性治疗。
Objective To investigate the changes of bacterial spectrum in acute bacterial conjunctivitis in C hina. Methods Secretion specimens were taken from the inferior conjunctiva surface of 50 eyes of 50 patients with acute bacterial conjunctivitis. Gram ＇s stain and bacterial culture were done. After 5 days of administration of 10 g·L（-1） azithromycin eye drops,bacterial cultures were tested again 3 days later. Results Bacterial culture positive rate was 80. 0%. 97. 5%of eyes showed Gram ＇s stain positive bacterium and most of them were staphylococcus epidermidis（72. 5%）,including 2 cases with oxacillin-resistant Staphylococcus epidermidis. After 5 days of administration of anti-biotics,clinical symptoms in 94. 0% of the patients were gone. In 60.0% of the cases,the pathogenic bacteria were completely eliminated,while in 5. 0% of the cases,they were partly eliminated. Staphylococcus epidermidis was still the main bacterium in the re-test（56. 2%）. Conclusion The most prevalent bacterium of acute bacterial conjunctivitis in China is staphylococcus epidermidis,in which more attentions should be paid and targeted treatment should be given.
出处
《眼科新进展》
CAS
北大核心
2016年第3期281-282,287,共3页
Recent Advances in Ophthalmology
关键词
急性细菌性结膜炎
细菌培养
表皮葡萄球菌
acute bacterial conjunctivitis
bacterial culture
staphylococcus epidermidis
